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TYK2 licenses non-canonical inflammasome activation during endotoxemia.
Poelzl A, Lassnig C, Tangermann S, Hromadová D, Reichart U, Gawish R, Mueller K, Moriggl R, Linkermann A, Glösmann M, Kenner L, Mueller M, Strobl B. Poelzl A, et al. Cell Death Differ. 2021 Feb;28(2):748-763. doi: 10.1038/s41418-020-00621-x. Epub 2020 Sep 14. Cell Death Differ. 2021. PMID: 32929218 Free PMC article.
Oncogenic TYK2 P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade.
Woess K, Macho-Maschler S, Van Ingen Schenau DS, Butler M, Lassnig C, Valcanover D, Poelzl A, Meissl K, Maurer B, Brandstoetter T, Vogl C, Koren A, Kubicek S, Orlova A, Moriggl R, Strobl B, Sexl V, Van Leeuwen FN, Kuiper RP, Mueller M. Woess K, et al. Among authors: poelzl a. Haematologica. 2023 Apr 1;108(4):993-1005. doi: 10.3324/haematol.2021.279848. Haematologica. 2023. PMID: 35021603 Free PMC article.
STAT1 Isoforms Differentially Regulate NK Cell Maturation and Anti-tumor Activity.
Meissl K, Simonović N, Amenitsch L, Witalisz-Siepracka A, Klein K, Lassnig C, Puga A, Vogl C, Poelzl A, Bosmann M, Dohnal A, Sexl V, Müller M, Strobl B. Meissl K, et al. Among authors: poelzl a. Front Immunol. 2020 Sep 11;11:2189. doi: 10.3389/fimmu.2020.02189. eCollection 2020. Front Immunol. 2020. PMID: 33042133 Free PMC article.
Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1.
Gawish R, Bulat T, Biaggio M, Lassnig C, Bago-Horvath Z, Macho-Maschler S, Poelzl A, Simonović N, Prchal-Murphy M, Rom R, Amenitsch L, Ferrarese L, Kornhoff J, Lederer T, Svinka J, Eferl R, Bosmann M, Kalinke U, Stoiber D, Sexl V, Krmpotić A, Jonjić S, Müller M, Strobl B. Gawish R, et al. Among authors: poelzl a. Cell Rep. 2019 Feb 26;26(9):2394-2406.e5. doi: 10.1016/j.celrep.2019.02.017. Cell Rep. 2019. PMID: 30811989 Free PMC article.
Testicular niche required for human spermatogonial stem cell expansion.
Smith JF, Yango P, Altman E, Choudhry S, Poelzl A, Zamah AM, Rosen M, Klatsky PC, Tran ND. Smith JF, et al. Among authors: poelzl a. Stem Cells Transl Med. 2014 Sep;3(9):1043-54. doi: 10.5966/sctm.2014-0045. Epub 2014 Jul 18. Stem Cells Transl Med. 2014. PMID: 25038247 Free PMC article.