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All-d-Enantiomeric Peptide D3 Designed for Alzheimer's Disease Treatment Dynamically Interacts with Membrane-Bound Amyloid-β Precursors.
Bocharov EV, Gremer L, Urban AS, Okhrimenko IS, Volynsky PE, Nadezhdin KD, Bocharova OV, Kornilov DA, Zagryadskaya YA, Kamynina AV, Kuzmichev PK, Kutzsche J, Bolakhrif N, Müller-Schiffmann A, Dencher NA, Arseniev AS, Efremov RG, Gordeliy VI, Willbold D. Bocharov EV, et al. Among authors: urban as. J Med Chem. 2021 Nov 25;64(22):16464-16479. doi: 10.1021/acs.jmedchem.1c00632. Epub 2021 Nov 5. J Med Chem. 2021. PMID: 34739758
Transmembrane Peptides as a New Strategy to Inhibit Neuraminidase-1 Activation.
Albrecht C, Kuznetsov AS, Appert-Collin A, Dhaideh Z, Callewaert M, Bershatsky YV, Urban AS, Bocharov EV, Bagnard D, Baud S, Blaise S, Romier-Crouzet B, Efremov RG, Dauchez M, Duca L, Gueroult M, Maurice P, Bennasroune A. Albrecht C, et al. Among authors: urban as. Front Cell Dev Biol. 2020 Dec 16;8:611121. doi: 10.3389/fcell.2020.611121. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33392200 Free PMC article.
Atomistic mechanism of the constitutive activation of PDGFRA via its transmembrane domain.
Polyansky AA, Bocharov EV, Velghe AI, Kuznetsov AS, Bocharova OV, Urban AS, Arseniev AS, Zagrovic B, Demoulin JB, Efremov RG. Polyansky AA, et al. Among authors: urban as. Biochim Biophys Acta Gen Subj. 2019 Jan;1863(1):82-95. doi: 10.1016/j.bbagen.2018.09.011. Epub 2018 Sep 22. Biochim Biophys Acta Gen Subj. 2019. PMID: 30253204
Diplocloster agilis gen. nov., sp. nov. and Diplocloster modestus sp. nov., two novel anaerobic fermentative members of Lachnospiraceae isolated from human faeces.
Chaplin AV, Shcherbakova VA, Pikina AP, Sokolova SR, Korzhanova M, Belova VA, Korostin DO, Rebrikov DV, Kardonsky DA, Urban AS, Zakharzhevskaya NB, Suzina NE, Podoprigora IV, Das MS, Kholopova DO, Efimov BA. Chaplin AV, et al. Among authors: urban as. Int J Syst Evol Microbiol. 2022 Feb;72(2). doi: 10.1099/ijsem.0.005222. Int J Syst Evol Microbiol. 2022. PMID: 35133260
Dimeric states of transmembrane domains of insulin and IGF-1R receptors: Structures and possible role in activation.
Kuznetsov AS, Zamaletdinov MF, Bershatsky YV, Urban AS, Bocharova OV, Bennasroune A, Maurice P, Bocharov EV, Efremov RG. Kuznetsov AS, et al. Among authors: urban as. Biochim Biophys Acta Biomembr. 2020 Nov 1;1862(11):183417. doi: 10.1016/j.bbamem.2020.183417. Epub 2020 Jul 23. Biochim Biophys Acta Biomembr. 2020. PMID: 32710851 Free article.
Familial L723P Mutation Can Shift the Distribution between the Alternative APP Transmembrane Domain Cleavage Cascades by Local Unfolding of the Ε-Cleavage Site Suggesting a Straightforward Mechanism of Alzheimer's Disease Pathogenesis.
Bocharov EV, Nadezhdin KD, Urban AS, Volynsky PE, Pavlov KV, Efremov RG, Arseniev AS, Bocharova OV. Bocharov EV, et al. Among authors: urban as. ACS Chem Biol. 2019 Jul 19;14(7):1573-1582. doi: 10.1021/acschembio.9b00309. Epub 2019 Jun 19. ACS Chem Biol. 2019. PMID: 31180641