Receptor-destroying enzyme (RDE) from Vibrio cholerae modulates IgE activity and reduces the initiation of anaphylaxis.
Yamazaki T, Inui M, Hiemori K, Tomono S, Itoh M, Ichimonji I, Nakashima A, Takagi H, Biswas M, Izawa K, Kitaura J, Imai T, Sugiura N, Tateno H, Akashi-Takamura S.
Yamazaki T, et al.
J Biol Chem. 2019 Apr 26;294(17):6659-6669. doi: 10.1074/jbc.RA118.006375. Epub 2019 Mar 4.
J Biol Chem. 2019.
PMID: 30833330
Free PMC article.
Therefore, IgE is a major target for managing allergies. Previous studies have reported that oligomannose on IgE can be a potential target to inhibit allergic responses. ...To reveal the mechanism by which RDE (II) interferes with IgE activity, we performed l …
Therefore, IgE is a major target for managing allergies. Previous studies have reported that oligomannose on IgE can be a pote …