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Showing results for amino abdulkarim
Your search for Amina Abdulkarim retrieved no results
Metabotropic glutamate receptors as drug targets.
Récasens M, Guiramand J, Aimar R, Abdulkarim A, Barbanel G. Récasens M, et al. Curr Drug Targets. 2007 May;8(5):651-81. doi: 10.2174/138945007780618544. Curr Drug Targets. 2007. PMID: 17504108 Review.
L-glutamate (Glu), the main excitatory amino acid neurotransmitter in the mammalian central nervous system, is involved in many physiological functions, including learning and memory, but also in toxic phenomena occurring in numerous degenerative or neurological diseases. …
L-glutamate (Glu), the main excitatory amino acid neurotransmitter in the mammalian central nervous system, is involved in many physi …
Novel Fluticasone Propionate and Salmeterol Fixed-Dose Combination Nano-Encapsulated Particles Using Polyamide Based on L-Lysine.
Alyami MH, Dahmash EZ, Ali DK, Alyami HS, AbdulKarim H, Alsudir SA. Alyami MH, et al. Pharmaceuticals (Basel). 2022 Mar 8;15(3):321. doi: 10.3390/ph15030321. Pharmaceuticals (Basel). 2022. PMID: 35337119 Free PMC article.
Herein, a one-step approach is presented to expedite the synthesis of nanoaggregates made from a biocompatible and biodegradable polyamide based on L-lysine amino acid employing market-leading active pharmaceutical ingredients (fluticasone propionate (FP) and salmeterol xi …
Herein, a one-step approach is presented to expedite the synthesis of nanoaggregates made from a biocompatible and biodegradable polyamide b …
pIChemiSt ─ Free Tool for the Calculation of Isoelectric Points of Modified Peptides.
Frolov AI, Chankeshwara SV, Abdulkarim Z, Ghiandoni GM. Frolov AI, et al. J Chem Inf Model. 2023 Jan 9;63(1):187-196. doi: 10.1021/acs.jcim.2c01261. Epub 2022 Dec 27. J Chem Inf Model. 2023. PMID: 36573842 Free PMC article.
Different pK(a) sets are published in the literature for natural amino acids, however, they are insufficient to describe synthetically modified peptides, complex peptides of natural origin, and peptides conjugated with structures of other modalities. ...
Different pK(a) sets are published in the literature for natural amino acids, however, they are insufficient to describe syntheticall …
Zinc N,N-bis(2-picolyl)amine Chelates Show Substitution-Dependent Cleavage of Phosphodiesters in Models as Well as of PNAzyme-RNA Bulges.
Svenningsen SW, Luige O, Abdulkarim Z, Strömberg R, Williams NH. Svenningsen SW, et al. Molecules. 2024 May 3;29(9):2123. doi: 10.3390/molecules29092123. Molecules. 2024. PMID: 38731616 Free PMC article.
In the present study, we introduce a series of metal chelating groups based on N,N-bis(2-picolyl) groups (parent, 6-methyl and 6-amino substituted) as the active sites of novel PNAzymes. An improved synthetic route for the 6-amino analogues is described. The catalyt …
In the present study, we introduce a series of metal chelating groups based on N,N-bis(2-picolyl) groups (parent, 6-methyl and 6-amino …
Mutants of EF-Tu defective in binding aminoacyl-tRNA.
Abdulkarim F, Ehrenberg M, Hughes D. Abdulkarim F, et al. FEBS Lett. 1996 Mar 18;382(3):297-303. doi: 10.1016/0014-5793(96)00184-6. FEBS Lett. 1996. PMID: 8605989 Free article.
Five single amino acid substitution variants of EF-Tu from Salmonella typhimurium were tested for their ability to promote poly(U)-translation in vitro. ...Fourth, missense errors are increased as well as decreased by the different amino acid substitutions. Finally, …
Five single amino acid substitution variants of EF-Tu from Salmonella typhimurium were tested for their ability to promote poly(U)-tr …
A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and Microcephaly.
Abdulkarim B, Nicolino M, Igoillo-Esteve M, Daures M, Romero S, Philippi A, Senée V, Lopes M, Cunha DA, Harding HP, Derbois C, Bendelac N, Hattersley AT, Eizirik DL, Ron D, Cnop M, Julier C. Abdulkarim B, et al. Diabetes. 2015 Nov;64(11):3951-62. doi: 10.2337/db15-0477. Epub 2015 Jul 9. Diabetes. 2015. PMID: 26159176 Free PMC article.
Here, we report the first homozygous mutation in the PPP1R15B gene (also known as constitutive repressor of eIF2alpha phosphorylation [CReP]) encoding the regulatory subunit of an eIF2alpha-specific phosphatase in two siblings affected by a novel syndrome of diabetes of youth wit …
Here, we report the first homozygous mutation in the PPP1R15B gene (also known as constitutive repressor of eIF2alpha phosphorylation [CReP] …
Functional EF-Tu with large C-terminal extensions in an E coli strain with a precise deletion of both chromosomal tuf genes.
Schnell R, Abdulkarim F, Kálmán M, Isaksson LA. Schnell R, et al. FEBS Lett. 2003 Mar 13;538(1-3):139-44. doi: 10.1016/s0014-5793(03)00159-5. FEBS Lett. 2003. PMID: 12633867 Free article.
By using plasmid replacement, based on plasmid incompatibility, mutant EF-Tu variants with a large C'-terminal extension up to 270 amino acids were studied and proved to be functional in a strain lacking the chromosomal tufA and tufB genes....
By using plasmid replacement, based on plasmid incompatibility, mutant EF-Tu variants with a large C'-terminal extension up to 270 amino …
Amniotic fluid: the value of prenatal analysis. 1.
Abdul-Karim RW, Beydoun SN. Abdul-Karim RW, et al. Postgrad Med. 1972 Aug;52(2):147-9 passim. doi: 10.1080/00325481.1972.11713215. Postgrad Med. 1972. PMID: 5065357 No abstract available.
Mutations to kirromycin resistance occur in the interface of domains I and III of EF-Tu.GTP.
Abdulkarim F, Liljas L, Hughes D. Abdulkarim F, et al. FEBS Lett. 1994 Sep 26;352(2):118-22. doi: 10.1016/0014-5793(94)00937-6. FEBS Lett. 1994. PMID: 7925958 Free article.
We have isolated and sequenced a collection of kirromycin resistant tuf mutations and identified thirteen single amino acid substitutions at seven different sites in EF-Tu. These have been mapped onto the 3D structures of EF-Tu.GTP and EF-Tu.GDP. ...
We have isolated and sequenced a collection of kirromycin resistant tuf mutations and identified thirteen single amino acid substitut …
13 results