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Year Number of Results
2012 1
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2015 5
2016 4
2018 1
2020 4
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2022 2
2024 0

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18 results

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Page 1
A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases.
Ghigo A, Murabito A, Sala V, Pisano AR, Bertolini S, Gianotti A, Caci E, Montresor A, Premchandar A, Pirozzi F, Ren K, Della Sala A, Mergiotti M, Richter W, de Poel E, Matthey M, Caldrer S, Cardone RA, Civiletti F, Costamagna A, Quinney NL, Butnarasu C, Visentin S, Ruggiero MR, Baroni S, Crich SG, Ramel D, Laffargue M, Tocchetti CG, Levi R, Conti M, Lu XY, Melotti P, Sorio C, De Rose V, Facchinetti F, Fanelli V, Wenzel D, Fleischmann BK, Mall MA, Beekman J, Laudanna C, Gentzsch M, Lukacs GL, Pedemonte N, Hirsch E. Ghigo A, et al. Among authors: gianotti a. Sci Transl Med. 2022 Mar 30;14(638):eabl6328. doi: 10.1126/scitranslmed.abl6328. Epub 2022 Mar 30. Sci Transl Med. 2022. PMID: 35353541 Free PMC article.
Lack of Kcnn4 improves mucociliary clearance in muco-obstructive lung disease.
Vega G, Guequén A, Philp AR, Gianotti A, Arzola L, Villalón M, Zegarra-Moran O, Galietta LJ, Mall MA, Flores CA. Vega G, et al. Among authors: gianotti a. JCI Insight. 2020 Aug 20;5(16):e140076. doi: 10.1172/jci.insight.140076. JCI Insight. 2020. PMID: 32814712 Free PMC article.
Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel.
Pedemonte N, Bertozzi F, Caci E, Sorana F, Di Fruscia P, Tomati V, Ferrera L, Rodríguez-Gimeno A, Berti F, Pesce E, Sondo E, Gianotti A, Scudieri P, Bandiera T, Galietta LJV. Pedemonte N, et al. Among authors: gianotti a. Sci Adv. 2020 Feb 21;6(8):eaay9669. doi: 10.1126/sciadv.aay9669. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32128418 Free PMC article.
Identification, Structure-Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators.
Brindani N, Gianotti A, Giovani S, Giacomina F, Di Fruscia P, Sorana F, Bertozzi SM, Ottonello G, Goldoni L, Penna I, Russo D, Summa M, Bertorelli R, Ferrera L, Pesce E, Sondo E, Galietta LJV, Bandiera T, Pedemonte N, Bertozzi F. Brindani N, et al. Among authors: gianotti a. J Med Chem. 2020 Oct 8;63(19):11169-11194. doi: 10.1021/acs.jmedchem.0c01050. Epub 2020 Sep 18. J Med Chem. 2020. PMID: 32946228 Free PMC article.
Goblet Cell Hyperplasia Requires High Bicarbonate Transport To Support Mucin Release.
Gorrieri G, Scudieri P, Caci E, Schiavon M, Tomati V, Sirci F, Napolitano F, Carrella D, Gianotti A, Musante I, Favia M, Casavola V, Guerra L, Rea F, Ravazzolo R, Di Bernardo D, Galietta LJ. Gorrieri G, et al. Among authors: gianotti a. Sci Rep. 2016 Oct 27;6:36016. doi: 10.1038/srep36016. Sci Rep. 2016. PMID: 27786259 Free PMC article.
Upregulation of TMEM16A Protein in Bronchial Epithelial Cells by Bacterial Pyocyanin.
Caci E, Scudieri P, Di Carlo E, Morelli P, Bruno S, De Fino I, Bragonzi A, Gianotti A, Sondo E, Ferrera L, Palleschi A, Santambrogio L, Ravazzolo R, Galietta LJ. Caci E, et al. Among authors: gianotti a. PLoS One. 2015 Jun 29;10(6):e0131775. doi: 10.1371/journal.pone.0131775. eCollection 2015. PLoS One. 2015. PMID: 26121472 Free PMC article.
18 results