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Page 1
Showing results for amine suzuki
Search for Amane Suzuki instead (3 results)
Aminative Suzuki-Miyaura coupling.
Onnuch P, Ramagonolla K, Liu RY. Onnuch P, et al. Science. 2024 Mar;383(6686):1019-1024. doi: 10.1126/science.adl5359. Epub 2024 Feb 29. Science. 2024. PMID: 38422125
The Suzuki-Miyaura and Buchwald-Hartwig coupling reactions are widely used to form carbon-carbon (C-C) and carbon-nitrogen (C-N) bonds, respectively. We report the incorporation of a formal nitrene insertion process into the Suzuki-Miyaura reaction, altering the pro …
The Suzuki-Miyaura and Buchwald-Hartwig coupling reactions are widely used to form carbon-carbon (C-C) and carbon-nitrogen (C-N) bond …
Groebke-Blackburn-Bienaymé Reaction for DNA-Encoded Library Technology.
An Y, Lee J, Seo H, Bae S, Kang J, Lee J, Kim J, Nam MH, Song M, Hwang GT. An Y, et al. Org Lett. 2023 Jun 23;25(24):4445-4450. doi: 10.1021/acs.orglett.3c01366. Epub 2023 Jun 13. Org Lett. 2023. PMID: 37310879
This study presents a DNA-compatible synthesis of diverse 5-arylimidazo[1,2-a]pyridin-3-amine derivatives using the Suzuki-Miyaura reaction, followed by a Groebke-Blackburn-Bienayme (GBB) reaction. ...
This study presents a DNA-compatible synthesis of diverse 5-arylimidazo[1,2-a]pyridin-3-amine derivatives using the Suzuki-Miy …
Electrochemically Enabled, Nickel-Catalyzed Amination.
Li C, Kawamata Y, Nakamura H, Vantourout JC, Liu Z, Hou Q, Bao D, Starr JT, Chen J, Yan M, Baran PS. Li C, et al. Angew Chem Int Ed Engl. 2017 Oct 9;56(42):13088-13093. doi: 10.1002/anie.201707906. Epub 2017 Sep 14. Angew Chem Int Ed Engl. 2017. PMID: 28834098 Free PMC article.
Along with amide bond formation, Suzuki cross-coupling, and reductive amination, the Buchwald-Hartwig-Ullmann-type amination of aryl halides stands as one of the most employed reactions in modern medicinal chemistry. ...Of note is the scalability, functional- …
Along with amide bond formation, Suzuki cross-coupling, and reductive amination, the Buchwald-Hartwig-Ullmann-type aminatio
N-(3,4-dimethoxyphenethyl)-6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine inhibits bladder cancer progression by suppressing YAP1/TAZ.
Shiraishi Y, Maehama T, Nishio M, Otani J, Hikasa H, Mak TW, Sasaki T, Honma T, Kondoh Y, Osada H, Yoshida M, Fujisawa M, Suzuki A. Shiraishi Y, et al. Genes Cells. 2022 Oct;27(10):602-612. doi: 10.1111/gtc.12979. Epub 2022 Aug 22. Genes Cells. 2022. PMID: 36054428 Free article.
Accessing data from our previous screening of a chemical library of compounds targeting the Hippo pathway, we identified DMPCA (N-(3,4-dimethoxyphenethyl)-6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine) as an agent able to induce the phosphorylation of LATS1 and YAP1/TAZ …
Accessing data from our previous screening of a chemical library of compounds targeting the Hippo pathway, we identified DMPCA (N-(3,4-dimet …
Stereoconvergent amine-directed alkyl-alkyl Suzuki reactions of unactivated secondary alkyl chlorides.
Lu Z, Wilsily A, Fu GC. Lu Z, et al. J Am Chem Soc. 2011 Jun 1;133(21):8154-7. doi: 10.1021/ja203560q. Epub 2011 May 10. J Am Chem Soc. 2011. PMID: 21553917 Free PMC article.
A new family of stereoconvergent cross-couplings of unactivated secondary alkyl electrophiles has been developed, specifically, arylamine-directed alkyl-alkyl Suzuki reactions. This represents the first such investigation to be focused on the use of alkyl chlorides as subs …
A new family of stereoconvergent cross-couplings of unactivated secondary alkyl electrophiles has been developed, specifically, arylamine-di …
Old drug fluvoxamine, new hope for COVID-19.
Hashimoto Y, Suzuki T, Hashimoto K. Hashimoto Y, et al. Eur Arch Psychiatry Clin Neurosci. 2022 Feb;272(1):161-163. doi: 10.1007/s00406-021-01326-z. Epub 2021 Sep 2. Eur Arch Psychiatry Clin Neurosci. 2022. PMID: 34476589 Free PMC article. No abstract available.
Trifluoromethoxypyrazines: Preparation and Properties.
Sokolenko TM, Yagupolskii YL. Sokolenko TM, et al. Molecules. 2020 May 9;25(9):2226. doi: 10.3390/molecules25092226. Molecules. 2020. PMID: 32397388 Free PMC article.
As trifluoromethoxy-substituted pyrazines are still unknown, we have developed efficient and scalable methods for 2-chloro-5-trifluoromethoxypyrazine synthesis, showing the synthetic utility of this molecule for Buchwald-Hartwig amination and the Kumada-Corriu and Suzuk
As trifluoromethoxy-substituted pyrazines are still unknown, we have developed efficient and scalable methods for 2-chloro-5-trifluoromethox …
5,311 results