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Children's Oncology Group Trial AALL1231: A Phase III Clinical Trial Testing Bortezomib in Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia and Lymphoma.
Teachey DT, Devidas M, Wood BL, Chen Z, Hayashi RJ, Hermiston ML, Annett RD, Archer JH, Asselin BL, August KJ, Cho SY, Dunsmore KP, Fisher BT, Freedman JL, Galardy PJ, Harker-Murray P, Horton TM, Jaju AI, Lam A, Messinger YH, Miles RR, Okada M, Patel SI, Schafer ES, Schechter T, Singh N, Steele AC, Sulis ML, Vargas SL, Winter SS, Wood C, Zweidler-McKay P, Bollard CM, Loh ML, Hunger SP, Raetz EA. Teachey DT, et al. J Clin Oncol. 2022 Jul 1;40(19):2106-2118. doi: 10.1200/JCO.21.02678. Epub 2022 Mar 10. J Clin Oncol. 2022. PMID: 35271306 Free PMC article. Clinical Trial.
The 4-year event-free survival (EFS) and overall survival (OS) for arm A (no bortezomib) versus arm B (bortezomib) were 80.1% 2.3% versus 83.8% 2.1% (EFS, P = .131) and 85.7% 2.0% versus 88.3% 1.8% (OS, P = .085). Patients with T-LL had improved EFS and OS with bort …
The 4-year event-free survival (EFS) and overall survival (OS) for arm A (no bortezomib) versus arm B (bortezomib) were 80.1% 2.3% versus 83 …
Conflict of Interest Disclosures.
[No authors listed] [No authors listed] Global Spine J. 2023 May;13(2_suppl):568S-591S. doi: 10.1177/21925682231173597. Global Spine J. 2023. PMID: 37222100 Free PMC article. No abstract available.
Advances in bioconversion of spent tea leaves to value-added products.
Negi T, Kumar Y, Sirohi R, Singh S, Tarafdar A, Pareek S, Kumar Awasthi M, Alok Sagar N. Negi T, et al. Bioresour Technol. 2022 Feb;346:126409. doi: 10.1016/j.biortech.2021.126409. Epub 2021 Nov 25. Bioresour Technol. 2022. PMID: 34838972 Review.
STL are rich in essential amino acids, omega-6 and omega-3 fatty acids, alkaloids (theobromine and caffeine), polyphenols (catechin, theaflavins and rutin) and minerals (Ca, P, K, Mg, Mn) that could be utilized for the production of industrially important products. ...
STL are rich in essential amino acids, omega-6 and omega-3 fatty acids, alkaloids (theobromine and caffeine), polyphenols (catechin, theafla …
Guidelines for the management of ocular trauma during the COVID-19 pandemic.
Natarajan S, Nair AG, Hegde R, Sundar G, Bapaye MM, Mukherjee G, Bhasin P, Sachdev MS, Sharma N, Sinha R; AIOS Writing Group: Alok Sen, Ashok Kumar Grover, Bhaskar Srinivasan, Jeevan S. Titiyal, Jayanta Kumar Das, Kasturi Bhattacharjee, Kim Ramasamy, J K S Parihar, Mehul Shah, O P Agrawal, Prashant Bawankule, Rajiv Raman, Ruchir Mehta, Rupesh Agrawal, Sanjiv Mohan, Shakeen Singh , Thirumalesh M.B., Usha Kim, Vinod Kumar Baranwal. Natarajan S, et al. Indian J Ophthalmol. 2020 Nov;68(11):2483-2485. doi: 10.4103/ijo.IJO_1892_20. Indian J Ophthalmol. 2020. PMID: 33120648 Free PMC article.
4 Dimensional XStrain speckle tracking echocardiography: comprehensive evaluation of left ventricular strain and twist parameters in healthy Indian adults during COVID-19 pandemic.
Mehrotra A, Kacker S, Shadab M, Chandra N, Singh AK. Mehrotra A, et al. Am J Cardiovasc Dis. 2022 Aug 15;12(4):192-204. eCollection 2022. Am J Cardiovasc Dis. 2022. PMID: 36147787 Free PMC article.
METHOD: Study population consisted of 80 adults of 18-60 years (58 men, 22 women), which was arbitrarily divided into two groups: Group A <30 years and Group B >31 years. RESULTS: GLS was higher in females (P<0.01) and in Group A (P<0.01). On the contrar …
METHOD: Study population consisted of 80 adults of 18-60 years (58 men, 22 women), which was arbitrarily divided into two groups: Group A &l …
Evaluation of Gasless Laparoscopy as a Tool for Minimal Access Surgery in Low-to Middle-Income Countries: A Phase II Noninferiority Randomized Controlled Study.
Mishra A, Bains L, Jesudin G, Aruparayil N, Singh R, Shashi. Mishra A, et al. J Am Coll Surg. 2020 Nov;231(5):511-519. doi: 10.1016/j.jamcollsurg.2020.07.783. Epub 2020 Aug 19. J Am Coll Surg. 2020. PMID: 32827645 Free PMC article. Clinical Trial.

No significant difference was observed in the mean operating time between the GAL group (52.9 minutes) and the COL group (55 minutes) (p = 0.3). Intraoperative vital signs were better in the GAL group (p < 0.05). The postoperative pain score was slightly higher i

No significant difference was observed in the mean operating time between the GAL group (52.9 minutes) and the COL group (55 minutes) (p
Variation of body fat percentage with special reference to diet modification in patients with chronic kidney disease: a longitudinal study.
Srivastava N, Singh RG, Alok K, Singh S. Srivastava N, et al. Saudi J Kidney Dis Transpl. 2014 Jul;25(4):793-800. doi: 10.4103/1319-2442.135008. Saudi J Kidney Dis Transpl. 2014. PMID: 24969190
No significant change was seen in BFP, waist circumference (WC) and BMI at BS and at TM. There was significant improvement in serum albumin (P <0.05) and e-GFR (P <0.01) while CRP was elevated both at BL and TM. The dietary intake was within the prescribed lim …
No significant change was seen in BFP, waist circumference (WC) and BMI at BS and at TM. There was significant improvement in serum albumin …
Endophytes of opium poppy differentially modulate host plant productivity and genes for the biosynthetic pathway of benzylisoquinoline alkaloids.
Pandey SS, Singh S, Babu CS, Shanker K, Srivastava NK, Kalra A. Pandey SS, et al. Planta. 2016 May;243(5):1097-114. doi: 10.1007/s00425-016-2467-9. Epub 2016 Jan 21. Planta. 2016. PMID: 26794966
It was evident that the endophytes from leaf were involved in improving photosynthetic efficiency, and thus crop growth and yield and the endophytes from capsule were involved in enhancing BIA biosynthesis. Capsule endophytes of alkaloid-rich P. somniferum cv. Sampada enha …
It was evident that the endophytes from leaf were involved in improving photosynthetic efficiency, and thus crop growth and yield and the en …
12 results