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Page 1
Time-resolved crystallography captures light-driven DNA repair.
Christou NE, Apostolopoulou V, Melo DVM, Ruppert M, Fadini A, Henkel A, Sprenger J, Oberthuer D, Günther S, Pateras A, Rahmani Mashhour A, Yefanov OM, Galchenkova M, Reinke PYA, Kremling V, Scheer TES, Lange ER, Middendorf P, Schubert R, De Zitter E, Lumbao-Conradson K, Herrmann J, Rahighi S, Kunavar A, Beale EV, Beale JH, Cirelli C, Johnson PJM, Dworkowski F, Ozerov D, Bertrand Q, Wranik M, Bacellar C, Bajt S, Wakatsuki S, Sellberg JA, Huse N, Turk D, Chapman HN, Lane TJ. Christou NE, et al. Among authors: fadini a. Science. 2023 Dec;382(6674):1015-1020. doi: 10.1126/science.adj4270. Epub 2023 Nov 30. Science. 2023. PMID: 38033070
Optical control of ultrafast structural dynamics in a fluorescent protein.
Hutchison CDM, Baxter JM, Fitzpatrick A, Dorlhiac G, Fadini A, Perrett S, Maghlaoui K, Lefèvre SB, Cordon-Preciado V, Ferreira JL, Chukhutsina VU, Garratt D, Barnard J, Galinis G, Glencross F, Morgan RM, Stockton S, Taylor B, Yuan L, Romei MG, Lin CY, Marangos JP, Schmidt M, Chatrchyan V, Buckup T, Morozov D, Park J, Park S, Eom I, Kim M, Jang D, Choi H, Hyun H, Park G, Nango E, Tanaka R, Owada S, Tono K, DePonte DP, Carbajo S, Seaberg M, Aquila A, Boutet S, Barty A, Iwata S, Boxer SG, Groenhof G, van Thor JJ. Hutchison CDM, et al. Among authors: fadini a. Nat Chem. 2023 Nov;15(11):1607-1615. doi: 10.1038/s41557-023-01275-1. Epub 2023 Aug 10. Nat Chem. 2023. PMID: 37563326 Free PMC article.
Serial Femtosecond Crystallography Reveals that Photoactivation in a Fluorescent Protein Proceeds via the Hula Twist Mechanism.
Fadini A, Hutchison CDM, Morozov D, Chang J, Maghlaoui K, Perrett S, Luo F, Kho JCX, Romei MG, Morgan RML, Orr CM, Cordon-Preciado V, Fujiwara T, Nuemket N, Tosha T, Tanaka R, Owada S, Tono K, Iwata S, Boxer SG, Groenhof G, Nango E, van Thor JJ. Fadini A, et al. J Am Chem Soc. 2023 Jul 26;145(29):15796-15808. doi: 10.1021/jacs.3c02313. Epub 2023 Jul 7. J Am Chem Soc. 2023. PMID: 37418747 Free PMC article.
Kilohertz droplet-on-demand serial femtosecond crystallography at the European XFEL station FXE.
Perrett S, Fadini A, Hutchison CDM, Bhattacharya S, Morrison C, Turkot O, Jakobsen MB, Größler M, Licón-Saláiz J, Griese F, Flewett S, Valerio J, Schulz J, Biednov M, Jiang Y, Han H, Yousef H, Khakhulin D, Milne C, Barty A, van Thor JJ. Perrett S, et al. Among authors: fadini a. Struct Dyn. 2024 Apr 17;11(2):024310. doi: 10.1063/4.0000248. eCollection 2024 Mar. Struct Dyn. 2024. PMID: 38638699 Free PMC article.
Power Density Titration of Reversible Photoisomerization of a Fluorescent Protein Chromophore in the Presence of Thermally Driven Barrier Crossing Shown by Quantitative Millisecond Serial Synchrotron X-ray Crystallography.
Baxter JM, Hutchison CDM, Fadini A, Maghlaoui K, Cordon-Preciado V, Morgan RML, Agthe M, Horrell S, Tellkamp F, Mehrabi P, Pfeifer Y, Müller-Werkmeister HM, von Stetten D, Pearson AR, van Thor JJ. Baxter JM, et al. Among authors: fadini a. J Am Chem Soc. 2024 Jun 7. doi: 10.1021/jacs.3c12883. Online ahead of print. J Am Chem Soc. 2024. PMID: 38848551