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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2008 2
2009 2
2010 5
2011 2
2012 2
2014 2
2015 4
2017 1
2018 3
2019 1
2020 2
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2022 2
2023 1
2024 2

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29 results

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Page 1
Divalent nanobodies to platelet CLEC-2 can serve as agonists or antagonists.
Clark JC, Martin EM, Morán LA, Di Y, Wang X, Zuidscherwoude M, Brown HC, Kavanagh DM, Hummert J, Eble JA, Nieswandt B, Stegner D, Pollitt AY, Herten DP, Tomlinson MG, García A, Watson SP. Clark JC, et al. Among authors: pollitt ay. Commun Biol. 2023 Apr 7;6(1):376. doi: 10.1038/s42003-023-04766-6. Commun Biol. 2023. PMID: 37029319 Free PMC article.
Katacine Is a New Ligand of CLEC-2 that Acts as a Platelet Agonist.
Morán LA, Di Y, Sowa MA, Hermida-Nogueira L, Barrachina MN, Martin E, Clark JC, Mize TH, Eble JA, Moreira D, Pollitt AY, Loza MI, Domínguez E, Watson SP, García Á. Morán LA, et al. Among authors: pollitt ay. Thromb Haemost. 2022 Aug;122(8):1361-1368. doi: 10.1055/a-1772-1069. Epub 2022 Feb 15. Thromb Haemost. 2022. PMID: 35170009 Free PMC article.
Low-dose Btk inhibitors selectively block platelet activation by CLEC-2.
Nicolson PLR, Nock SH, Hinds J, Garcia-Quintanilla L, Smith CW, Campos J, Brill A, Pike JA, Khan AO, Poulter NS, Kavanagh DM, Watson S, Watson CN, Clifford H, Huissoon AP, Pollitt AY, Eble JA, Pratt G, Watson SP, Hughes CE. Nicolson PLR, et al. Among authors: pollitt ay. Haematologica. 2021 Jan 1;106(1):208-219. doi: 10.3324/haematol.2019.218545. Haematologica. 2021. PMID: 31949019 Free PMC article.
CLEC-2 activates Syk through dimerization.
Hughes CE, Pollitt AY, Mori J, Eble JA, Tomlinson MG, Hartwig JH, O'Callaghan CA, Fütterer K, Watson SP. Hughes CE, et al. Among authors: pollitt ay. Blood. 2010 Apr 8;115(14):2947-55. doi: 10.1182/blood-2009-08-237834. Epub 2010 Feb 12. Blood. 2010. PMID: 20154219 Free PMC article.
CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development.
Finney BA, Schweighoffer E, Navarro-Núñez L, Bénézech C, Barone F, Hughes CE, Langan SA, Lowe KL, Pollitt AY, Mourao-Sa D, Sheardown S, Nash GB, Smithers N, Reis e Sousa C, Tybulewicz VL, Watson SP. Finney BA, et al. Among authors: pollitt ay. Blood. 2012 Feb 16;119(7):1747-56. doi: 10.1182/blood-2011-09-380709. Epub 2011 Dec 20. Blood. 2012. PMID: 22186994 Free PMC article.
Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation.
Dunster JL, Unsworth AJ, Bye AP, Haining EJ, Sowa MA, Di Y, Sage T, Pallini C, Pike JA, Hardy AT, Nieswandt B, García Á, Watson SP, Poulter NS, Gibbins JM, Pollitt AY. Dunster JL, et al. Among authors: pollitt ay. J Thromb Haemost. 2020 Feb;18(2):485-496. doi: 10.1111/jth.14673. Epub 2019 Dec 6. J Thromb Haemost. 2020. PMID: 31680418 Free PMC article.
29 results