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Re-growth of Mycobacterium tuberculosis populations exposed to antibiotic combinations is due to the presence of isoniazid and not bacterial growth rate.
Hendon-Dunn CL, Pertinez H, Marriott AAN, Hatch K, Allnutt JC, Davies G, Bacon J. Hendon-Dunn CL, et al. Among authors: marriott aan. Antimicrob Agents Chemother. 2019 Sep 9;63(12):e00570-19. doi: 10.1128/AAC.00570-19. Epub 2019 Sep 16. Antimicrob Agents Chemother. 2019. PMID: 31527023 Free PMC article.
Non-replicating Mycobacterium tuberculosis elicits a reduced infectivity profile with corresponding modifications to the cell wall and extracellular matrix.
Bacon J, Alderwick LJ, Allnutt JA, Gabasova E, Watson R, Hatch KA, Clark SO, Jeeves RE, Marriott A, Rayner E, Tolley H, Pearson G, Hall G, Besra GS, Wernisch L, Williams A, Marsh PD. Bacon J, et al. Among authors: marriott a. PLoS One. 2014 Feb 6;9(2):e87329. doi: 10.1371/journal.pone.0087329. eCollection 2014. PLoS One. 2014. PMID: 24516549 Free PMC article.
Mycobacterium tuberculosis Is Resistant to Isoniazid at a Slow Growth Rate by Single Nucleotide Polymorphisms in katG Codon Ser315.
Jeeves RE, Marriott AA, Pullan ST, Hatch KA, Allnutt JC, Freire-Martin I, Hendon-Dunn CL, Watson R, Witney AA, Tyler RH, Arnold C, Marsh PD, McHugh TD, Bacon J. Jeeves RE, et al. Among authors: marriott aa. PLoS One. 2015 Sep 18;10(9):e0138253. doi: 10.1371/journal.pone.0138253. eCollection 2015. PLoS One. 2015. PMID: 26382066 Free PMC article.
A Flow Cytometry Method for Rapidly Assessing Mycobacterium tuberculosis Responses to Antibiotics with Different Modes of Action.
Hendon-Dunn CL, Doris KS, Thomas SR, Allnutt JC, Marriott AA, Hatch KA, Watson RJ, Bottley G, Marsh PD, Taylor SC, Bacon J. Hendon-Dunn CL, et al. Among authors: marriott aa. Antimicrob Agents Chemother. 2016 Jun 20;60(7):3869-83. doi: 10.1128/AAC.02712-15. Print 2016 Jul. Antimicrob Agents Chemother. 2016. PMID: 26902767 Free PMC article.