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Sterile inflammation via TRPM8 RNA-dependent TLR3-NF-kB/IRF3 activation promotes antitumor immunity in prostate cancer.
Alaimo A, Genovesi S, Annesi N, De Felice D, Subedi S, Macchia A, La Manna F, Ciani Y, Vannuccini F, Mugoni V, Notarangelo M, Libergoli M, Broso F, Taulli R, Ala U, Savino A, Cortese M, Mirzaaghaei S, Poli V, Bonapace IM, Papotti MG, Molinaro L, Doglioni C, Caffo O, Anesi A, Nagler M, Bertalot G, Carbone FG, Barbareschi M, Basso U, Dassi E, Pizzato M, Romanel A, Demichelis F, Kruithof-de Julio M, Lunardi A. Alaimo A, et al. Among authors: macchia a. EMBO J. 2024 Mar;43(5):780-805. doi: 10.1038/s44318-024-00040-5. Epub 2024 Feb 5. EMBO J. 2024. PMID: 38316991 Free PMC article.
PI3K-regulated Glycine N-methyltransferase is required for the development of prostate cancer.
Zabala-Letona A, Arruabarrena-Aristorena A, Fernandez-Ruiz S, Viera C, Carlevaris O, Ercilla A, Mendizabal I, Martin T, Macchia A, Camacho L, Pujana-Vaquerizo M, Sanchez-Mosquera P, Torrano V, Martin-Martin N, Zuniga-Garcia P, Castillo-Martin M, Ugalde-Olano A, Loizaga-Iriarte A, Unda M, Mato JM, Berra E, Martinez-Chantar ML, Carracedo A. Zabala-Letona A, et al. Among authors: macchia a. Oncogenesis. 2022 Feb 23;11(1):10. doi: 10.1038/s41389-022-00382-x. Oncogenesis. 2022. PMID: 35197445 Free PMC article.
Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors.
Alaimo A, Lorenzoni M, Ambrosino P, Bertossi A, Bisio A, Macchia A, Zoni E, Genovesi S, Cambuli F, Foletto V, De Felice D, Soldovieri MV, Mosca I, Gandolfi F, Brunelli M, Petris G, Cereseto A, Villarroel A, Thalmann G, Carbone FG, Kruithof-de Julio M, Barbareschi M, Romanel A, Taglialatela M, Lunardi A. Alaimo A, et al. Among authors: macchia a. Cell Death Dis. 2020 Dec 7;11(12):1039. doi: 10.1038/s41419-020-03256-5. Cell Death Dis. 2020. PMID: 33288740 Free PMC article.
PGC1α Suppresses Prostate Cancer Cell Invasion through ERRα Transcriptional Control.
Valcarcel-Jimenez L, Macchia A, Crosas-Molist E, Schaub-Clerigué A, Camacho L, Martín-Martín N, Cicogna P, Viera-Bardón C, Fernández-Ruiz S, Rodriguez-Hernandez I, Hermanova I, Astobiza I, Cortazar AR, Corres-Mendizabal J, Gomez-Muñoz A, Sanz-Moreno V, Torrano V, Carracedo A. Valcarcel-Jimenez L, et al. Among authors: macchia a. Cancer Res. 2019 Dec 15;79(24):6153-6165. doi: 10.1158/0008-5472.CAN-19-1231. Epub 2019 Oct 8. Cancer Res. 2019. PMID: 31594836
Genomic and Functional Regulation of TRIB1 Contributes to Prostate Cancer Pathogenesis.
Shahrouzi P, Astobiza I, Cortazar AR, Torrano V, Macchia A, Flores JM, Niespolo C, Mendizabal I, Caloto R, Ercilla A, Camacho L, Arreal L, Bizkarguenaga M, Martinez-Chantar ML, Bustelo XR, Berra E, Kiss-Toth E, Velasco G, Zabala-Letona A, Carracedo A. Shahrouzi P, et al. Among authors: macchia a. Cancers (Basel). 2020 Sep 11;12(9):2593. doi: 10.3390/cancers12092593. Cancers (Basel). 2020. PMID: 32932846 Free PMC article.
Integrative analysis of transcriptomics and clinical data uncovers the tumor-suppressive activity of MITF in prostate cancer.
Valcarcel-Jimenez L, Macchia A, Martín-Martín N, Cortazar AR, Schaub-Clerigué A, Pujana-Vaquerizo M, Fernández-Ruiz S, Lacasa-Viscasillas I, Santos-Martin A, Loizaga-Iriarte A, Unda-Urzaiz M, Hermanova I, Astobiza I, Graupera M, Starkova J, Sutherland J, Barrio R, Aransay AM, Carracedo A, Torrano V. Valcarcel-Jimenez L, et al. Among authors: macchia a. Cell Death Dis. 2018 Oct 11;9(10):1041. doi: 10.1038/s41419-018-1096-6. Cell Death Dis. 2018. PMID: 30310055 Free PMC article.