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Discovery of Trace Amine Associated Receptor 1 (TAAR1) Agonist 2-(5-(4'-Chloro-[1,1'-biphenyl]-4-yl)-4H-1,2,4-triazol-3-yl)ethan-1-amine (LK00764) for the Treatment of Psychotic Disorders.
Krasavin M, Lukin A, Sukhanov I, Gerasimov AS, Kuvarzin S, Efimova EV, Dorofeikova M, Nichugovskaya A, Matveev A, Onokhin K, Zakharov K, Gureev M, Gainetdinov RR. Krasavin M, et al. Among authors: lukin a. Biomolecules. 2022 Nov 7;12(11):1650. doi: 10.3390/biom12111650. Biomolecules. 2022. PMID: 36359001 Free PMC article.
Discovery and In Vivo Efficacy of Trace Amine-Associated Receptor 1 (TAAR1) Agonist 4-(2-Aminoethyl)-N-(3,5-dimethylphenyl)piperidine-1-carboxamide Hydrochloride (AP163) for the Treatment of Psychotic Disorders.
Krasavin M, Peshkov AA, Lukin A, Komarova K, Vinogradova L, Smirnova D, Kanov EV, Kuvarzin SR, Murtazina RZ, Efimova EV, Gureev M, Onokhin K, Zakharov K, Gainetdinov RR. Krasavin M, et al. Among authors: lukin a. Int J Mol Sci. 2022 Sep 30;23(19):11579. doi: 10.3390/ijms231911579. Int J Mol Sci. 2022. PMID: 36232878 Free PMC article.
Discovery of polar spirocyclic orally bioavailable urea inhibitors of soluble epoxide hydrolase.
Lukin A, Kramer J, Hartmann M, Weizel L, Hernandez-Olmos V, Falahati K, Burghardt I, Kalinchenkova N, Bagnyukova D, Zhurilo N, Rautio J, Forsberg M, Ihalainen J, Auriola S, Leppänen J, Konstantinov I, Pogoryelov D, Proschak E, Dar'in D, Krasavin M. Lukin A, et al. Bioorg Chem. 2018 Oct;80:655-667. doi: 10.1016/j.bioorg.2018.07.014. Epub 2018 Jul 17. Bioorg Chem. 2018. PMID: 30059891
11 results