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Page 1
The 26S proteasome is a multifaceted target for anti-cancer therapies.
Grigoreva TA, Tribulovich VG, Garabadzhiu AV, Melino G, Barlev NA. Grigoreva TA, et al. Among authors: garabadzhiu av. Oncotarget. 2015 Sep 22;6(28):24733-49. doi: 10.18632/oncotarget.4619. Oncotarget. 2015. PMID: 26295307 Free PMC article. Review.
Proapoptotic modification of substituted isoindolinones as MDM2-p53 inhibitors.
Grigoreva TA, Novikova DS, Petukhov AV, Gureev MA, Garabadzhiu AV, Melino G, Barlev NA, Tribulovich VG. Grigoreva TA, et al. Among authors: garabadzhiu av. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5197-5202. doi: 10.1016/j.bmcl.2017.10.049. Epub 2017 Oct 20. Bioorg Med Chem Lett. 2017. PMID: 29089230
Molecular dynamics of the full-length p53 monomer.
Chillemi G, Davidovich P, D'Abramo M, Mametnabiev T, Garabadzhiu AV, Desideri A, Melino G. Chillemi G, et al. Among authors: garabadzhiu av. Cell Cycle. 2013 Sep 15;12(18):3098-108. doi: 10.4161/cc.26162. Epub 2013 Sep 5. Cell Cycle. 2013. PMID: 23974096 Free PMC article.
Design, in silico prioritization and biological profiling of apoptosis-inducing lactams amenable by the Castagnoli-Cushman reaction.
Krasavin M, Gureyev MA, Dar'in D, Bakulina O, Chizhova M, Lepikhina A, Novikova D, Grigoreva T, Ivanov G, Zhumagalieva A, Garabadzhiu AV, Tribulovich VG. Krasavin M, et al. Among authors: garabadzhiu av. Bioorg Med Chem. 2018 May 15;26(9):2651-2673. doi: 10.1016/j.bmc.2018.04.036. Epub 2018 Apr 18. Bioorg Med Chem. 2018. PMID: 29691156