A Non-Invasive Medical Device for Parkinson's Patients with Episodes of Freezing of Gait

Sensors (Basel). 2019 Feb 12;19(3):737. doi: 10.3390/s19030737.

Abstract

A critical symptom of Parkinson's disease (PD) is the occurrence of Freezing of Gait (FOG), an episodic disorder that causes frequent falls and consequential injuries in PD patients. There are various auditory, visual, tactile, and other types of stimulation interventions that can be used to induce PD patients to escape FOG episodes. In this article, we describe a low cost wearable system for non-invasive gait monitoring and external delivery of superficial vibratory stimulation to the lower extremities triggered by FOG episodes. The intended purpose is to reduce the duration of the FOG episode, thus allowing prompt resumption of gait to prevent major injuries. The system, based on an Android mobile application, uses a tri-axial accelerometer device for gait data acquisition. Gathered data is processed via a discrete wavelet transform-based algorithm that precisely detects FOG episodes in real time. Detection activates external vibratory stimulation of the legs to reduce FOG time. The integration of detection and stimulation in one low cost device is the chief novel contribution of this work. We present analyses of sensitivity, specificity and effectiveness of the proposed system to validate its usefulness.

Keywords: Parkinson’s disease; clinical assessment; discrete wavelet transform; freezing of gait; neurodegenerative disorders; sensors; vibratory stimulus.

MeSH terms

  • Accelerometry / methods
  • Aged
  • Aged, 80 and over
  • Algorithms
  • Equipment and Supplies
  • Female
  • Gait / physiology*
  • Gait Disorders, Neurologic / physiopathology*
  • Humans
  • Lower Extremity / physiopathology
  • Male
  • Middle Aged
  • Monitoring, Physiologic / instrumentation*
  • Parkinson Disease / physiopathology*
  • Physical Functional Performance
  • Sensitivity and Specificity
  • Wavelet Analysis