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Combined induction of mTOR-dependent and mTOR-independent pathways of autophagy activation as an experimental therapy for Alzheimer's disease-like pathology in a mouse model.
Pupyshev AB, Belichenko VM, Tenditnik MV, Bashirzade AA, Dubrovina NI, Ovsyukova MV, Akopyan AA, Fedoseeva LA, Korolenko TA, Amstislavskaya TG, Tikhonova MA. Pupyshev AB, et al. Pharmacol Biochem Behav. 2022 Jun;217:173406. doi: 10.1016/j.pbb.2022.173406. Epub 2022 May 21. Pharmacol Biochem Behav. 2022. PMID: 35609863
Comparative analysis of early neurodegeneration signs in a mouse model of Alzheimer's disease-like pathology induced by two types of the central (Intracerebroventricular vs. Intrahippocampal) administration of Aβ25-35 oligomers.
Belichenko VM, Bashirzade AA, Tenditnik MV, Dubrovina NI, Akopyan AA, Ovsyukova MV, Fedoseeva LA, Pupyshev AB, Aftanas LI, Amstislavskaya TG, Tikhonova MA. Belichenko VM, et al. Among authors: pupyshev ab. Behav Brain Res. 2023 Oct 2;454:114651. doi: 10.1016/j.bbr.2023.114651. Epub 2023 Aug 30. Behav Brain Res. 2023. PMID: 37657512
Treatment with Autophagy Inducer Trehalose Alleviates Memory and Behavioral Impairments and Neuroinflammatory Brain Processes in db/db Mice.
Korolenko TA, Dubrovina NI, Ovsyukova MV, Bgatova NP, Tenditnik MV, Pupyshev AB, Akopyan AA, Goncharova NV, Lin CL, Zavjalov EL, Tikhonova MA, Amstislavskaya TG. Korolenko TA, et al. Among authors: pupyshev ab. Cells. 2021 Sep 27;10(10):2557. doi: 10.3390/cells10102557. Cells. 2021. PMID: 34685538 Free PMC article.