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Page 1
Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models.
ACS Med Chem Lett. 2020 Feb 13;11(5):754-759. doi: 10.1021/acsmedchemlett.9b00604. eCollection 2020 May 14.
ACS Med Chem Lett. 2020.
PMID: 32435381
Free PMC article.
Enrichment of DNA replication intermediates by EdU pull down.
Pessina F, Romussi A, Piccini D, Mazzucco G, Varasi M, Doksani Y.
Pessina F, et al. Among authors: romussi a.
Methods Cell Biol. 2024;182:83-94. doi: 10.1016/bs.mcb.2022.11.001. Epub 2022 Dec 13.
Methods Cell Biol. 2024.
PMID: 38359989
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Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration.
Sartori L, Mercurio C, Amigoni F, Cappa A, Fagá G, Fattori R, Legnaghi E, Ciossani G, Mattevi A, Meroni G, Moretti L, Cecatiello V, Pasqualato S, Romussi A, Thaler F, Trifiró P, Villa M, Vultaggio S, Botrugno OA, Dessanti P, Minucci S, Zagarrí E, Carettoni D, Iuzzolino L, Varasi M, Vianello P.
Sartori L, et al. Among authors: romussi a.
J Med Chem. 2017 Mar 9;60(5):1673-1692. doi: 10.1021/acs.jmedchem.6b01018. Epub 2017 Feb 27.
J Med Chem. 2017.
PMID: 28186755
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Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.
Vianello P, Sartori L, Amigoni F, Cappa A, Fagá G, Fattori R, Legnaghi E, Ciossani G, Mattevi A, Meroni G, Moretti L, Cecatiello V, Pasqualato S, Romussi A, Thaler F, Trifiró P, Villa M, Botrugno OA, Dessanti P, Minucci S, Vultaggio S, Zagarrí E, Varasi M, Mercurio C.
Vianello P, et al. Among authors: romussi a.
J Med Chem. 2017 Mar 9;60(5):1693-1715. doi: 10.1021/acs.jmedchem.6b01019. Epub 2017 Feb 27.
J Med Chem. 2017.
PMID: 28186757
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New selective phosphodiesterase 4D inhibitors differently acting on long, short, and supershort isoforms.
Bruno O, Romussi A, Spallarossa A, Brullo C, Schenone S, Bondavalli F, Vanthuyne N, Roussel C.
Bruno O, et al. Among authors: romussi a.
J Med Chem. 2009 Nov 12;52(21):6546-57. doi: 10.1021/jm900977c.
J Med Chem. 2009.
PMID: 19827751
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Relative stereochemistry of a diterpene from Salvia cinnabarina.
Bisio A, Pagano B, Romussi A, Bruno O, De Tommasi N, Romussi G, Mattia CA.
Bisio A, et al. Among authors: romussi a.
Molecules. 2007 Oct 10;12(10):2279-87. doi: 10.3390/12102279.
Molecules. 2007.
PMID: 17978757
Free PMC article.
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New insights into selective PDE4D inhibitors: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) oxime (GEBR-7b) structural development and promising activities to restore memory impairment.
Brullo C, Ricciarelli R, Prickaerts J, Arancio O, Massa M, Rotolo C, Romussi A, Rebosio C, Marengo B, Pronzato MA, van Hagen BTJ, van Goethem NP, D'Ursi P, Orro A, Milanesi L, Guariento S, Cichero E, Fossa P, Fedele E, Bruno O.
Brullo C, et al. Among authors: romussi a.
Eur J Med Chem. 2016 Nov 29;124:82-102. doi: 10.1016/j.ejmech.2016.08.018. Epub 2016 Aug 13.
Eur J Med Chem. 2016.
PMID: 27560284
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