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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 2
1989 1
1991 1
1992 1
1993 5
1994 4
1995 8
1996 3
1997 8
1998 25
1999 25
2000 39
2001 54
2002 109
2003 137
2004 128
2005 129
2006 165
2007 167
2008 155
2009 179
2010 195
2011 204
2012 217
2013 196
2014 250
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2024 197

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5,326 results

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The following term was not found in PubMed: Girona-Ruiz
Page 1
Treatment of actinic keratosis: a systematic review.
Worley B, Harikumar V, Reynolds K, Dirr MA, Christensen RE, Anvery N, Yi MD, Poon E, Alam M. Worley B, et al. Arch Dermatol Res. 2023 Jul;315(5):1099-1108. doi: 10.1007/s00403-022-02490-5. Epub 2022 Dec 1. Arch Dermatol Res. 2023. PMID: 36454335 Review.
The greatest degree of improvement was seen with photodynamic therapy (PDT) used adjunctively with other modalities, but this was not significantly different compared to other treatments. PDT, cryotherapy, imiquimod, ingenol mebutate (IMB), 5-fluorouracil (5-FU), trichloro …
The greatest degree of improvement was seen with photodynamic therapy (PDT) used adjunctively with other modalities, but this was not signif …
Allosteric inhibition of SHP2 uncovers aberrant TLR7 trafficking in aggravating psoriasis.
Zhu Y, Wu Z, Yan W, Shao F, Ke B, Jiang X, Gao J, Guo W, Lai Y, Ma H, Chen D, Xu Q, Sun Y. Zhu Y, et al. EMBO Mol Med. 2022 Mar 7;14(3):e14455. doi: 10.15252/emmm.202114455. Epub 2021 Dec 22. EMBO Mol Med. 2022. PMID: 34936223 Free PMC article.
We found that the Src homology-2 domain-containing protein tyrosine phosphatase-2 (SHP2) was highly expressed in both psoriatic patients and imiquimod (IMQ)-induced psoriasis-like mice. Also, the SHP2 allosteric inhibitor SHP099 reduced pro-inflammatory cytokine expression …
We found that the Src homology-2 domain-containing protein tyrosine phosphatase-2 (SHP2) was highly expressed in both psoriatic patients and …
Pharmacological Agents Used in the Prevention and Treatment of Actinic Keratosis: A Review.
Arcuri D, Ramchatesingh B, Lagacé F, Iannattone L, Netchiporouk E, Lefrançois P, Litvinov IV. Arcuri D, et al. Int J Mol Sci. 2023 Mar 5;24(5):4989. doi: 10.3390/ijms24054989. Int J Mol Sci. 2023. PMID: 36902419 Free PMC article. Review.
Topical 5-FU, including combination formulations with either calcipotriol or salicylic acid, as well as imiquimod, diclofenac and photodynamic light therapy are all accepted treatment strategies employed to target and eliminate AKs. ...Topical diclofenac (3%) appears to be …
Topical 5-FU, including combination formulations with either calcipotriol or salicylic acid, as well as imiquimod, diclofenac and pho …
Nanoparticle-Enhanced Radiotherapy to Trigger Robust Cancer Immunotherapy.
Chen Q, Chen J, Yang Z, Xu J, Xu L, Liang C, Han X, Liu Z. Chen Q, et al. Adv Mater. 2019 Mar;31(10):e1802228. doi: 10.1002/adma.201802228. Epub 2019 Jan 21. Adv Mater. 2019. PMID: 30663118
Herein, core-shell nanoparticles based poly(lactic-co-glycolic) acid (PLGA) are fabricate, by encapsulating water-soluble catalase (Cat), an enzyme that can decompose H(2) O(2) to generate O(2) , inside the inner core, and loading hydrophobic imiquimod (R837), a Toll-like- …
Herein, core-shell nanoparticles based poly(lactic-co-glycolic) acid (PLGA) are fabricate, by encapsulating water-soluble catalase (Cat), an …
IL-23- and Imiquimod-Induced Models of Experimental Psoriasis in Mice.
Singh TP, Zhang HH, Hwang ST, Farber JM. Singh TP, et al. Curr Protoc Immunol. 2019 Jun;125(1):e71. doi: 10.1002/cpim.71. Epub 2019 Jan 7. Curr Protoc Immunol. 2019. PMID: 30615272
Genome-wide association studies have found that polymorphisms in genes for IL-23 and its receptor are important in psoriasis, and blocking IL-23 is an effective therapy in the disease. The use of Aldara() , a cream that contains the TLR7 and TLR8 agonist imiquimod ( …
Genome-wide association studies have found that polymorphisms in genes for IL-23 and its receptor are important in psoriasis, and blocking I …
IL-17A Promotes Psoriasis-Associated Keratinocyte Proliferation through ACT1-Dependent Activation of YAP-AREG Axis.
Yu Z, Yu Q, Xu H, Dai X, Yu Y, Cui L, Chen Y, Gu J, Zhang X, Guo C, Shi Y. Yu Z, et al. J Invest Dermatol. 2022 Sep;142(9):2343-2352. doi: 10.1016/j.jid.2022.02.016. Epub 2022 Mar 15. J Invest Dermatol. 2022. PMID: 35304250 Free article.
In this study, we show that the YAP-AREG pathway is activated in human psoriatic skin and is suppressed by IL-17A antagonist secukinumab and that imiquimod and IL-17A administration activates the YAP-AREG axis in mice epidermis. ...
In this study, we show that the YAP-AREG pathway is activated in human psoriatic skin and is suppressed by IL-17A antagonist secukinumab and …
Lidocaine Ameliorates Psoriasis by Obstructing Pathogenic CGRP Signaling‒Mediated Sensory Neuron‒Dendritic Cell Communication.
Yin Q, Sun L, Cai X, Lou F, Sun Y, Wang B, Jiang B, Bao L, Li X, Song N, Tang S, Bai J, Wang Z, Wu Y, Zhou H, Wang H, Yu B, Li Q, Wang H. Yin Q, et al. J Invest Dermatol. 2022 Aug;142(8):2173-2183.e6. doi: 10.1016/j.jid.2022.01.002. Epub 2022 Jan 12. J Invest Dermatol. 2022. PMID: 35032503 Free article.
Lidocaine treatment markedly reduced patients' clinical scores and improved an imiquimod-induced rat model of psoriasis as competent as systemic delivery of a TNF-alpha antibody. Imiquimod application elicited aberrant cutaneous nerve outgrowth and excessive generat …
Lidocaine treatment markedly reduced patients' clinical scores and improved an imiquimod-induced rat model of psoriasis as competent …
Management of Condyloma Acuminata in Pregnancy: A Review.
Sugai S, Nishijima K, Enomoto T. Sugai S, et al. Sex Transm Dis. 2021 Jun 1;48(6):403-409. doi: 10.1097/OLQ.0000000000001322. Sex Transm Dis. 2021. PMID: 33093288 Free PMC article.
The treatment methods described in the literature were laser therapy, cryotherapy, imiquimod, photodynamic therapy, trichloroacetic acid, and local hyperthermia. ...Based on our assessment of the literature, we recommend cryotherapy as the first-choice treatment and laser …
The treatment methods described in the literature were laser therapy, cryotherapy, imiquimod, photodynamic therapy, trichloroacetic a …
Estradiol suppresses psoriatic inflammation in mice by regulating neutrophil and macrophage functions.
Adachi A, Honda T, Egawa G, Kanameishi S, Takimoto R, Miyake T, Hossain MR, Komine M, Ohtsuki M, Gunzer M, Ikuta K, Kabashima K. Adachi A, et al. J Allergy Clin Immunol. 2022 Oct;150(4):909-919.e8. doi: 10.1016/j.jaci.2022.03.028. Epub 2022 May 16. J Allergy Clin Immunol. 2022. PMID: 35589416
OBJECTIVE: We studied whether estradiol, a female hormone, plays protective roles in imiquimod-induced psoriatic inflammation in mice by regulating neutrophil and macrophage functions. METHODS: Wild-type mice and conditional knockout mice were ovariectomized, supplemented …
OBJECTIVE: We studied whether estradiol, a female hormone, plays protective roles in imiquimod-induced psoriatic inflammation in mice …
FXYD3 enhances IL-17A signaling to promote psoriasis by competitively binding TRAF3 in keratinocytes.
Yang W, He R, Qu H, Lian W, Xue Y, Wang T, Lin W, Zhu P, Xia M, Lai L, Wang Q. Yang W, et al. Cell Mol Immunol. 2023 Mar;20(3):292-304. doi: 10.1038/s41423-023-00973-7. Epub 2023 Jan 25. Cell Mol Immunol. 2023. PMID: 36693922 Free PMC article.
Here, we show that the expression of FXYD3, a member of the FXYD domain-containing regulators of Na(+)/K(+) ATPases family, is significantly increased in the lesional skin of psoriasis patients and mice with imiquimod (IMQ)-induced psoriasis. IL-17A, a cytokine important f …
Here, we show that the expression of FXYD3, a member of the FXYD domain-containing regulators of Na(+)/K(+) ATPases family, is significantly …
5,326 results