Computational membrane biophysics: From ion channel interactions with drugs to cellular function.
Miranda WE, Ngo VA, Perissinotti LL, Noskov SY.
Miranda WE, et al.
Biochim Biophys Acta Proteins Proteom. 2017 Nov;1865(11 Pt B):1643-1653. doi: 10.1016/j.bbapap.2017.08.008. Epub 2017 Aug 26.
Biochim Biophys Acta Proteins Proteom. 2017.
PMID: 28847523
Free PMC article.
Review.
Deciphering the thermodynamics and kinetics of the ligand binding processes to these membrane proteins is at the heart of modern drug development. The ever-increasing computational power has already provided insightful data on the thermodynamics and kinetics of drug-target …
Deciphering the thermodynamics and kinetics of the ligand binding processes to these membrane proteins is at the heart of modern drug develo …