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Page 1
TH1902, a new docetaxel-peptide conjugate for the treatment of sortilin-positive triple-negative breast cancer.
Cancer Sci. 2021 Oct;112(10):4317-4334. doi: 10.1111/cas.15086. Epub 2021 Aug 12.
Cancer Sci. 2021.
PMID: 34314556
Free PMC article.
The Peptide-Drug Conjugate TH1902: A New Sortilin Receptor-Mediated Cancer Therapeutic against Ovarian and Endometrial Cancers.
Currie JC, Demeule M, Charfi C, Zgheib A, Larocque A, Danalache BA, Ouanouki A, Béliveau R, Marsolais C, Annabi B.
Currie JC, et al. Among authors: larocque a.
Cancers (Basel). 2022 Apr 8;14(8):1877. doi: 10.3390/cancers14081877.
Cancers (Basel). 2022.
PMID: 35454785
Free PMC article.
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Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties.
Demeule M, Beaudet N, Régina A, Besserer-Offroy É, Murza A, Tétreault P, Belleville K, Ché C, Larocque A, Thiot C, Béliveau R, Longpré JM, Marsault É, Leduc R, Lachowicz JE, Gonias SL, Castaigne JP, Sarret P.
Demeule M, et al. Among authors: larocque a.
J Clin Invest. 2014 Mar;124(3):1199-213. doi: 10.1172/JCI70647. Epub 2014 Feb 17.
J Clin Invest. 2014.
PMID: 24531547
Free PMC article.
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Use of a Noninvasive Brain-Penetrating Peptide-Drug Conjugate Strategy to Improve the Delivery of Opioid Pain Relief Medications to the Brain.
Eiselt É, Otis V, Belleville K, Yang G, Larocque A, Régina A, Demeule M, Sarret P, Gendron L.
Eiselt É, et al. Among authors: larocque a.
J Pharmacol Exp Ther. 2020 Jul;374(1):52-61. doi: 10.1124/jpet.119.263566. Epub 2020 Apr 23.
J Pharmacol Exp Ther. 2020.
PMID: 32327529
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New Peptide-Drug Conjugates for Precise Targeting of SORT1-Mediated Vasculogenic Mimicry in the Tumor Microenvironment of TNBC-Derived MDA-MB-231 Breast and Ovarian ES-2 Clear Cell Carcinoma Cells.
Charfi C, Demeule M, Currie JC, Larocque A, Zgheib A, Danalache BA, Ouanouki A, Béliveau R, Marsolais C, Annabi B.
Charfi C, et al. Among authors: larocque a.
Front Oncol. 2021 Oct 22;11:760787. doi: 10.3389/fonc.2021.760787. eCollection 2021.
Front Oncol. 2021.
PMID: 34751242
Free PMC article.
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