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Shorter sleep time relates to lower human defensin 5 secretion and compositional disturbance of the intestinal microbiota accompanied by decreased short-chain fatty acid production.
Shimizu Y, Yamamura R, Yokoi Y, Ayabe T, Ukawa S, Nakamura K, Okada E, Imae A, Nakagawa T, Tamakoshi A, Nakamura K. Shimizu Y, et al. Among authors: imae a. Gut Microbes. 2023 Jan-Dec;15(1):2190306. doi: 10.1080/19490976.2023.2190306. Gut Microbes. 2023. PMID: 36945116 Free PMC article.
Lower human defensin 5 in elderly people compared to middle-aged is associated with differences in the intestinal microbiota composition: the DOSANCO Health Study.
Shimizu Y, Nakamura K, Kikuchi M, Ukawa S, Nakamura K, Okada E, Imae A, Nakagawa T, Yamamura R, Tamakoshi A, Ayabe T. Shimizu Y, et al. Among authors: imae a. Geroscience. 2022 Apr;44(2):997-1009. doi: 10.1007/s11357-021-00398-y. Epub 2021 Jun 8. Geroscience. 2022. PMID: 34105106 Free PMC article.