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Page 1
Did you mean amit g. Thomas (1 results)?
Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug.
Rais R, Lemberg KM, Tenora L, Arwood ML, Pal A, Alt J, Wu Y, Lam J, Aguilar JMH, Zhao L, Peters DE, Tallon C, Pandey R, Thomas AG, Dash RP, Seiwert T, Majer P, Leone RD, Powell JD, Slusher BS. Rais R, et al. Among authors: thomas ag. Sci Adv. 2022 Nov 18;8(46):eabq5925. doi: 10.1126/sciadv.abq5925. Epub 2022 Nov 16. Sci Adv. 2022. PMID: 36383674 Free PMC article.
A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis.
Peters DE, Norris LD, Tenora L, Šnajdr I, Ponti AK, Zhu X, Sakamoto S, Veeravalli V, Pradhan M, Alt J, Thomas AG, Majer P, Rais R, McDonald C, Slusher BS. Peters DE, et al. Among authors: thomas ag. Sci Transl Med. 2023 Aug 9;15(708):eabn7491. doi: 10.1126/scitranslmed.abn7491. Epub 2023 Aug 9. Sci Transl Med. 2023. PMID: 37556558 Free PMC article.
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer's disease mouse model.
Tallon C, Bell BJ, Malvankar MM, Deme P, Nogueras-Ortiz C, Eren E, Thomas AG, Hollinger KR, Pal A, Mustapic M, Huang M, Coleman K, Joe TR, Rais R, Haughey NJ, Kapogiannis D, Slusher BS. Tallon C, et al. Among authors: thomas ag. Transl Neurodegener. 2023 Dec 4;12(1):56. doi: 10.1186/s40035-023-00383-9. Transl Neurodegener. 2023. PMID: 38049923 Free PMC article.
Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice.
Huang M, Tallon C, Zhu X, Huizar KDJ, Picciolini S, Thomas AG, Tenora L, Liyanage W, Rodà F, Gualerzi A, Kannan RM, Bedoni M, Rais R, Slusher BS. Huang M, et al. Among authors: thomas ag. Pharmaceutics. 2023 Sep 21;15(9):2364. doi: 10.3390/pharmaceutics15092364. Pharmaceutics. 2023. PMID: 37765332 Free PMC article.
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in murine Alzheimer's disease.
Tallon C, Bell BJ, Malvankar MM, Deme P, Nogueras-Ortiz C, Eren E, Thomas AG, Hollinger KR, Pal A, Mustapic M, Huang M, Coleman K, Joe TR, Rais R, Haughey NJ, Kapogiannis D, Slusher BS. Tallon C, et al. Among authors: thomas ag. Res Sq [Preprint]. 2023 Jul 18:rs.3.rs-3131295. doi: 10.21203/rs.3.rs-3131295/v1. Res Sq. 2023. PMID: 37502930 Free PMC article. Updated. Preprint.
Inhibition of neutral sphingomyelinase 2 promotes remyelination.
Yoo SW, Agarwal A, Smith MD, Khuder SS, Baxi EG, Thomas AG, Rojas C, Moniruzzaman M, Slusher BS, Bergles DE, Calabresi PA, Haughey NJ. Yoo SW, et al. Among authors: thomas ag. Sci Adv. 2020 Oct 2;6(40):eaba5210. doi: 10.1126/sciadv.aba5210. Print 2020 Oct. Sci Adv. 2020. PMID: 33008902 Free PMC article.
Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice.
Tallon C, Bell BJ, Sharma A, Pal A, Malvankar MM, Thomas AG, Yoo SW, Hollinger KR, Coleman K, Wilkinson EL, Kannan S, Haughey NJ, Kannan RM, Rais R, Slusher BS. Tallon C, et al. Among authors: thomas ag. Pharmaceutics. 2022 Sep 28;14(10):2066. doi: 10.3390/pharmaceutics14102066. Pharmaceutics. 2022. PMID: 36297501 Free PMC article.
73 results