Anxiolytic, Analgesic and Anti-Inflammatory Effects of Peptides Hmg 1b-2 and Hmg 1b-4 from the Sea Anemone Heteractis magnifica.
Gladkikh IN, Klimovich AA, Kalina RS, Kozhevnikova YV, Khasanov TA, Osmakov DI, Koshelev SG, Monastyrnaya MM, Andreev YA, Leychenko EV, Kozlov SA.
Gladkikh IN, et al.
Toxins (Basel). 2023 May 15;15(5):341. doi: 10.3390/toxins15050341.
Toxins (Basel). 2023.
PMID: 37235375
Free PMC article.
Two sea anemone toxins, native Hmg 1b-2 and recombinant Hmg 1b-4, both related to APETx-like peptides, inhibited the transient current component of human ASIC3-delta20 expressed in Xenopus laevis oocytes, but only Hmg 1b-2 inhibited the rat ASIC3 transient current. The Hmg …
Two sea anemone toxins, native Hmg 1b-2 and recombinant Hmg 1b-4, both related to APETx-like peptides, inhibited the transient current compo …