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Over-activated hemichannels: A possible therapeutic target for human diseases.
Retamal MA, Fernandez-Olivares A, Stehberg J. Retamal MA, et al. Among authors: fernandez olivares a. Biochim Biophys Acta Mol Basis Dis. 2021 Nov 1;1867(11):166232. doi: 10.1016/j.bbadis.2021.166232. Epub 2021 Aug 5. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 34363932 Free article. Review.
4-Hydroxynonenal induces Cx46 hemichannel inhibition through its carbonylation.
Retamal MA, Fiori MC, Fernandez-Olivares A, Linsambarth S, Peña F, Quintana D, Stehberg J, Altenberg GA. Retamal MA, et al. Among authors: fernandez olivares a. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Aug;1865(8):158705. doi: 10.1016/j.bbalip.2020.158705. Epub 2020 Mar 31. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32244060
Extracellular Cysteines Are Critical to Form Functional Cx46 Hemichannels.
Fernández-Olivares A, Durán-Jara E, Verdugo DA, Fiori MC, Altenberg GA, Stehberg J, Alfaro I, Calderón JF, Retamal MA. Fernández-Olivares A, et al. Int J Mol Sci. 2022 Jun 29;23(13):7252. doi: 10.3390/ijms23137252. Int J Mol Sci. 2022. PMID: 35806258 Free PMC article.