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A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor.
Dekan Z, Sianati S, Yousuf A, Sutcliffe KJ, Gillis A, Mallet C, Singh P, Jin AH, Wang AM, Mohammadi SA, Stewart M, Ratnayake R, Fontaine F, Lacey E, Piggott AM, Du YP, Canals M, Sessions RB, Kelly E, Capon RJ, Alewood PF, Christie MJ. Dekan Z, et al. Among authors: jin ah. Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22353-22358. doi: 10.1073/pnas.1908662116. Epub 2019 Oct 14. Proc Natl Acad Sci U S A. 2019. PMID: 31611414 Free PMC article.