Comprehensive tissue deconvolution of cell-free DNA by deep learning for disease diagnosis and monitoring.
Li S, Zeng W, Ni X, Liu Q, Li W, Stackpole ML, Zhou Y, Gower A, Krysan K, Ahuja P, Lu DS, Raman SS, Hsu W, Aberle DR, Magyar CE, French SW, Han SB, Garon EB, Agopian VG, Wong WH, Dubinett SM, Zhou XJ.
Li S, et al.
Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2305236120. doi: 10.1073/pnas.2305236120. Epub 2023 Jul 3.
Proc Natl Acad Sci U S A. 2023.
PMID: 37399400
Free PMC article.
We further demonstrated the clinical utilities of cfSort with two potential applications: aiding disease diagnosis and monitoring treatment side effects. The tissue-derived cfDNA fraction estimated from cfSort reflected the clinical outcomes of the patients. ...
We further demonstrated the clinical utilities of cfSort with two potential applications: aiding disease diagnosis and monitoring tre …