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Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses.
Scheibner D, Salaheldin AH, Bagato O, Zaeck LM, Mostafa A, Blohm U, Müller C, Eweas AF, Franzke K, Karger A, Schäfer A, Gischke M, Hoffmann D, Lerolle S, Li X, Abd El-Hamid HS, Veits J, Breithaupt A, Boons GJ, Matrosovich M, Finke S, Pleschka S, Mettenleiter TC, de Vries RP, Abdelwhab EM. Scheibner D, et al. Among authors: salaheldin ah. PLoS Pathog. 2023 Feb 6;19(2):e1011135. doi: 10.1371/journal.ppat.1011135. eCollection 2023 Feb. PLoS Pathog. 2023. PMID: 36745654 Free PMC article.
Genetic incompatibilities and reduced transmission in chickens may limit the evolution of reassortants between H9N2 and panzootic H5N8 clade 2.3.4.4 avian influenza virus showing high virulence for mammals.
Mostafa A, Blaurock C, Scheibner D, Müller C, Blohm U, Schäfer A, Gischke M, Salaheldin AH, Nooh HZ, Ali MA, Breithaupt A, Mettenleiter TC, Pleschka S, Abdelwhab EM. Mostafa A, et al. Among authors: salaheldin ah. Virus Evol. 2020 Oct 15;6(2):veaa077. doi: 10.1093/ve/veaa077. eCollection 2020 Jul. Virus Evol. 2020. PMID: 33343923 Free PMC article.
Insertion of Basic Amino Acids in the Hemagglutinin Cleavage Site of H4N2 Avian Influenza Virus (AIV)-Reduced Virus Fitness in Chickens is Restored by Reassortment with Highly Pathogenic H5N1 AIV.
Gischke M, Ulrich R, I Fatola O, Scheibner D, Salaheldin AH, Crossley B, Böttcher-Friebertshäuser E, Veits J, Mettenleiter TC, Abdelwhab EM. Gischke M, et al. Among authors: salaheldin ah. Int J Mol Sci. 2020 Mar 28;21(7):2353. doi: 10.3390/ijms21072353. Int J Mol Sci. 2020. PMID: 32231159 Free PMC article.
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