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Bayesian PBPK modeling using R/Stan/Torsten and Julia/SciML/Turing.Jl.
Elmokadem A, Zhang Y, Knab T, Jordie E, Gillespie WR. Elmokadem A, et al. CPT Pharmacometrics Syst Pharmacol. 2023 Mar;12(3):300-310. doi: 10.1002/psp4.12926. Epub 2023 Feb 5. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36661183 Free PMC article.
A Quantitative Modeling and Simulation Framework to Support Candidate and Dose Selection of Anti-SARS-CoV-2 Monoclonal Antibodies to Advance Bamlanivimab Into a First-in-Human Clinical Trial.
Chigutsa E, Jordie E, Riggs M, Nirula A, Elmokadem A, Knab T, Chien JY. Chigutsa E, et al. Among authors: elmokadem a. Clin Pharmacol Ther. 2022 Mar;111(3):595-604. doi: 10.1002/cpt.2459. Epub 2021 Nov 17. Clin Pharmacol Ther. 2022. PMID: 34687040 Free PMC article.
Low-dose empagliflozin as adjunct-to-insulin therapy in type 1 diabetes: A valid modelling and simulation analysis to confirm efficacy.
Perkins BA, Soleymanlou N, Rosenstock J, Skyler JS, Laffel LM, Liesenfeld KH, Neubacher D, Riggs MM, Johnston CK, Eudy-Byrne RJ, Elmokadem A, George JT, Marquard J, Nock V. Perkins BA, et al. Among authors: elmokadem a. Diabetes Obes Metab. 2020 Mar;22(3):427-433. doi: 10.1111/dom.13945. Epub 2020 Jan 21. Diabetes Obes Metab. 2020. PMID: 31858718 Free PMC article.