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Showing results for agrin agrin
Search for Agrina Agrina instead (1 results)
Agrin and LRP4 antibodies as new biomarkers of myasthenia gravis.
Yan M, Xing GL, Xiong WC, Mei L. Yan M, et al. Ann N Y Acad Sci. 2018 Feb;1413(1):126-135. doi: 10.1111/nyas.13573. Epub 2018 Jan 28. Ann N Y Acad Sci. 2018. PMID: 29377176 Review.
It is caused by antibodies against acetylcholine receptor and muscle-specific tyrosine kinase; however, some MG patients do not have antibodies against either of the proteins. Recent studies have revealed antibodies against agrin and its receptor LRP4-both critical for neu …
It is caused by antibodies against acetylcholine receptor and muscle-specific tyrosine kinase; however, some MG patients do not have antibod …
Agrin in the CNS: a protein in search of a function?
Smith MA, Hilgenberg LG. Smith MA, et al. Neuroreport. 2002 Aug 27;13(12):1485-95. doi: 10.1097/00001756-200208270-00001. Neuroreport. 2002. PMID: 12218692 Review.
Agrin is also present in the CNS. However, while its spatiotemporal pattern of expression is consistent with a function in neuron-neuron synapse formation, it also suggests a role for agrin in other aspects of neural tissue morphogenesis. ...Possible roles for ag …
Agrin is also present in the CNS. However, while its spatiotemporal pattern of expression is consistent with a function in neuron-neu …
Agrin-like proteins of the neuromuscular junction.
Patthy L, Nikolics K. Patthy L, et al. Neurochem Int. 1994 Apr;24(4):301-16. doi: 10.1016/0197-0186(94)90108-2. Neurochem Int. 1994. PMID: 8061595 Review.
Agrin, a molecule synthesized by motorneurons, plays a key role in the formation of the neuromuscular junction. Agrin is released from motoneurons at the axon terminal after anterograde axonal transport and binds to agrin receptors present on muscle cells. .. …
Agrin, a molecule synthesized by motorneurons, plays a key role in the formation of the neuromuscular junction. Agrin is relea …
Neural agrin: a synaptic stabiliser.
Ngo ST, Noakes PG, Phillips WD. Ngo ST, et al. Int J Biochem Cell Biol. 2007;39(5):863-7. doi: 10.1016/j.biocel.2006.10.012. Epub 2006 Oct 25. Int J Biochem Cell Biol. 2007. PMID: 17126587 Review.
Neural agrin is a heparan sulphate proteoglycan first defined by its ability to induce the clustering of acetylcholine receptors (AChRs) on cultured muscle cells. ...Here we briefly review some key mechanisms through which neural agrin acts to foster the formation o …
Neural agrin is a heparan sulphate proteoglycan first defined by its ability to induce the clustering of acetylcholine receptors (ACh …
Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex.
Xie T, Xu G, Liu Y, Quade B, Lin W, Bai XC. Xie T, et al. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2300453120. doi: 10.1073/pnas.2300453120. Epub 2023 May 30. Proc Natl Acad Sci U S A. 2023. PMID: 37252960 Free PMC article.
Distinct from most members of RTK family, MuSK activation requires not only its cognate ligand agrin but also its coreceptors LRP4. However, how agrin and LRP4 coactivate MuSK remains unclear. ...Our cryo-EM analyses therefore uncover the assembly mechanism of ag …
Distinct from most members of RTK family, MuSK activation requires not only its cognate ligand agrin but also its coreceptors LRP4. H …
Agrin isoforms and their role in synaptogenesis.
McMahan UJ, Horton SE, Werle MJ, Honig LS, Kröger S, Ruegg MA, Escher G. McMahan UJ, et al. Curr Opin Cell Biol. 1992 Oct;4(5):869-74. doi: 10.1016/0955-0674(92)90113-q. Curr Opin Cell Biol. 1992. PMID: 1329871 Free article. Review.
Agrin is thought to mediate the motor neuron-induced aggregation of synaptic proteins on the surface of muscle fibers at neuromuscular junctions. Recent experiments provide direct evidence in support of this hypothesis, reveal the nature of agrin immunoreactivity at …
Agrin is thought to mediate the motor neuron-induced aggregation of synaptic proteins on the surface of muscle fibers at neuromuscula …
Agrin Mediates Angiogenesis in the Tumor Microenvironment.
Chakraborty S, Njah K, Hong W. Chakraborty S, et al. Trends Cancer. 2020 Feb;6(2):81-85. doi: 10.1016/j.trecan.2019.12.002. Epub 2020 Jan 9. Trends Cancer. 2020. PMID: 32061308 Free article.
Several proteoglycans associate with cell surface receptors and regulate angiogenesis within the tumor microenvironment (TME). We highlight the recent discovery that the proteoglycan Agrin cross talks between the tumor and the endothelium to promote an angiogenesis privile …
Several proteoglycans associate with cell surface receptors and regulate angiogenesis within the tumor microenvironment (TME). We highlight …
Testing the agrin hypothesis.
Kleiman RJ, Reichardt LF. Kleiman RJ, et al. Cell. 1996 May 17;85(4):461-4. doi: 10.1016/s0092-8674(00)81245-3. Cell. 1996. PMID: 8653780 Free article. Review. No abstract available.
Agrin orchestrates synaptic differentiation at the vertebrate neuromuscular junction.
Ruegg MA, Bixby JL. Ruegg MA, et al. Trends Neurosci. 1998 Jan;21(1):22-7. doi: 10.1016/s0166-2236(97)01154-5. Trends Neurosci. 1998. PMID: 9464682 Free article. Review.
Recent advances implicate proteins such as dystroglycan, MuSK, and rapsyn in the transduction of agrin signals. Recently, additional functions of agrin have been discovered, including the upregulation of gene transcription in myonuclei and the control of presynaptic …
Recent advances implicate proteins such as dystroglycan, MuSK, and rapsyn in the transduction of agrin signals. Recently, additional …
Agrin Yes-associated Protein Promotes the Proliferation of Epicardial Cells.
Jing X, Liu B, Deng S, Du J, She Q. Jing X, et al. J Cardiovasc Pharmacol. 2021 Jan 1;77(1):94-99. doi: 10.1097/FJC.0000000000000926. J Cardiovasc Pharmacol. 2021. PMID: 33136763
The proportion of cells in G1/S/G2 phase was determined by flow cytometry. The results showed that agrin significantly increased the expression of ki67, pH3, and Aurora B in epicardial cells. Flow cytometry results showed that agrin significantly increased the propo …
The proportion of cells in G1/S/G2 phase was determined by flow cytometry. The results showed that agrin significantly increased the …
1,465 results