A zebrafish model of manganism reveals reversible and treatable symptoms that are independent of neurotoxicity.
Bakthavatsalam S, Das Sharma S, Sonawane M, Thirumalai V, Datta A.
Bakthavatsalam S, et al.
Dis Model Mech. 2014 Nov;7(11):1239-51. doi: 10.1242/dmm.016683. Epub 2014 Sep 26.
Dis Model Mech. 2014.
PMID: 25261567
Free PMC article.
Environmental and occupational exposure to high concentrations of Mn causes manganism, a well-defined movement disorder in humans, with symptoms resembling Parkinson's disease (PD). However, manganism is distinct from PD and the neural basis of its pathology is poorly unde …
Environmental and occupational exposure to high concentrations of Mn causes manganism, a well-defined movement disorder in humans, with symp …