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Page 1
Development of an in-vivo active reversible butyrylcholinesterase inhibitor.
Košak U, Brus B, Knez D, Šink R, Žakelj S, Trontelj J, Pišlar A, Šlenc J, Gobec M, Živin M, Tratnjek L, Perše M, Sałat K, Podkowa A, Filipek B, Nachon F, Brazzolotto X, Więckowska A, Malawska B, Stojan J, Raščan IM, Kos J, Coquelle N, Colletier JP, Gobec S. Košak U, et al. Among authors: podkowa a. Sci Rep. 2016 Dec 21;6:39495. doi: 10.1038/srep39495. Sci Rep. 2016. PMID: 28000737 Free PMC article.
Yerba Mate as a Source of Elements and Bioactive Compounds with Antioxidant Activity.
Rząsa-Duran E, Kryczyk-Poprawa A, Drabicki D, Podkowa A, Sułkowska-Ziaja K, Szewczyk A, Kała K, Opoka W, Zięba P, Fidurski M, Muszyńska B. Rząsa-Duran E, et al. Among authors: podkowa a. Antioxidants (Basel). 2022 Feb 12;11(2):371. doi: 10.3390/antiox11020371. Antioxidants (Basel). 2022. PMID: 35204253 Free PMC article.
Development of tricyclic N-benzyl-4-hydroxybutanamide derivatives as inhibitors of GABA transporters mGAT1-4 with anticonvulsant, antinociceptive, and antidepressant activity.
Zaręba P, Sałat K, Höfner GC, Łątka K, Bajda M, Latacz G, Kotniewicz K, Rapacz A, Podkowa A, Maj M, Jóźwiak K, Filipek B, Wanner KT, Malawska B, Kulig K. Zaręba P, et al. Among authors: podkowa a. Eur J Med Chem. 2021 Oct 5;221:113512. doi: 10.1016/j.ejmech.2021.113512. Epub 2021 May 4. Eur J Med Chem. 2021. PMID: 34015586
The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity.
Košak U, Brus B, Knez D, Žakelj S, Trontelj J, Pišlar A, Šink R, Jukič M, Živin M, Podkowa A, Nachon F, Brazzolotto X, Stojan J, Kos J, Coquelle N, Sałat K, Colletier JP, Gobec S. Košak U, et al. Among authors: podkowa a. J Med Chem. 2018 Jan 11;61(1):119-139. doi: 10.1021/acs.jmedchem.7b01086. Epub 2017 Dec 22. J Med Chem. 2018. PMID: 29227101
21 results