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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1975 1
1979 1
1980 2
1983 3
1984 3
1985 5
1986 3
1987 1
1988 2
1989 2
1990 3
1991 3
1992 1
1993 6
1994 2
1995 2
1996 6
1997 4
1998 7
1999 11
2000 3
2001 8
2002 9
2003 11
2004 9
2005 8
2006 13
2007 16
2008 16
2009 12
2010 14
2011 16
2012 19
2013 30
2014 24
2015 49
2016 47
2017 44
2018 46
2019 59
2020 40
2021 35
2022 42
2023 46
2024 12

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617 results

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Page 1
Showing results for adrian major
Search for Adrian Smagor instead (1 results)
PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1.
Glancy E, Wang C, Tuck E, Healy E, Amato S, Neikes HK, Mariani A, Mucha M, Vermeulen M, Pasini D, Bracken AP. Glancy E, et al. Mol Cell. 2023 May 4;83(9):1393-1411.e7. doi: 10.1016/j.molcel.2023.03.018. Epub 2023 Apr 7. Mol Cell. 2023. PMID: 37030288 Free PMC article.
Polycomb repressive complex 2 (PRC2) mediates H3K27me3 deposition, which is thought to recruit canonical PRC1 (cPRC1) via chromodomain-containing CBX proteins to promote stable repression of developmental genes. PRC2 forms two major subcomplexes, PRC2.1 and PRC2.2, but the …
Polycomb repressive complex 2 (PRC2) mediates H3K27me3 deposition, which is thought to recruit canonical PRC1 (cPRC1) via chromodomain-conta …
Targeting CD70 with cusatuzumab eliminates acute myeloid leukemia stem cells in patients treated with hypomethylating agents.
Riether C, Pabst T, Höpner S, Bacher U, Hinterbrandner M, Banz Y, Müller R, Manz MG, Gharib WH, Francisco D, Bruggmann R, van Rompaey L, Moshir M, Delahaye T, Gandini D, Erzeel E, Hultberg A, Fung S, de Haard H, Leupin N, Ochsenbein AF. Riether C, et al. Nat Med. 2020 Sep;26(9):1459-1467. doi: 10.1038/s41591-020-0910-8. Epub 2020 Jun 29. Nat Med. 2020. PMID: 32601337 Clinical Trial.
Acute myeloid leukemia (AML) is driven by leukemia stem cells (LSCs) that resist conventional chemotherapy and are the major cause of relapse(1,2). Hypomethylating agents (HMAs) are the standard of care in the treatment of older or unfit patients with AML, but responses ar …
Acute myeloid leukemia (AML) is driven by leukemia stem cells (LSCs) that resist conventional chemotherapy and are the major cause of …
The synapse: people, words and connections.
Tansey EM. Tansey EM. Neuronal Signal. 2022 Jun 8;6(2):NS20220017. doi: 10.1042/NS20220017. eCollection 2022 Jun. Neuronal Signal. 2022. PMID: 35813266 Free PMC article.
This paper provides a review of some of the major historical developments in synaptic research and neurotransmission since the first appearance of the word 'synapsis' in 1895. The key contributions and inter-relationships of several significant scientists and Nobel Laureat …
This paper provides a review of some of the major historical developments in synaptic research and neurotransmission since the first …
mTOR and Tumor Cachexia.
Duval AP, Jeanneret C, Santoro T, Dormond O. Duval AP, et al. Int J Mol Sci. 2018 Jul 30;19(8):2225. doi: 10.3390/ijms19082225. Int J Mol Sci. 2018. PMID: 30061533 Free PMC article. Review.
As cachexia is associated with increased morbidity and mortality in cancer patients, identifying the underlying mechanisms leading to cachexia is essential in order to design novel therapeutic strategies. The mechanistic target of rapamycin (mTOR) is a major intracellular …
As cachexia is associated with increased morbidity and mortality in cancer patients, identifying the underlying mechanisms leading to cachex …
Potential Role of Curcumin for the Treatment of Major Depressive Disorder.
Lopresti AL. Lopresti AL. CNS Drugs. 2022 Feb;36(2):123-141. doi: 10.1007/s40263-022-00901-9. Epub 2022 Feb 7. CNS Drugs. 2022. PMID: 35129813 Free PMC article. Review.
Curcumin is the major biologically active polyphenolic constituent in the turmeric plant (Curcuma longa) that has been shown to have antioxidant, anti-inflammatory, neuroprotective, anticancer, antimicrobial, and cardioprotective effects. ...
Curcumin is the major biologically active polyphenolic constituent in the turmeric plant (Curcuma longa) that has been shown to have …
Vaccines against malaria.
Hill AV. Hill AV. Philos Trans R Soc Lond B Biol Sci. 2011 Oct 12;366(1579):2806-14. doi: 10.1098/rstb.2011.0091. Philos Trans R Soc Lond B Biol Sci. 2011. PMID: 21893544 Free PMC article. Review.
There is no licenced vaccine against any human parasitic disease and Plasmodium falciparum malaria, a major cause of infectious mortality, presents a great challenge to vaccine developers. ...
There is no licenced vaccine against any human parasitic disease and Plasmodium falciparum malaria, a major cause of infectious morta …
Are implanted electronic devices hackable?
Alexander B, Haseeb S, Baranchuk A. Alexander B, et al. Trends Cardiovasc Med. 2019 Nov;29(8):476-480. doi: 10.1016/j.tcm.2018.11.011. Epub 2018 Nov 22. Trends Cardiovasc Med. 2019. PMID: 30482482 Review.
We outline the actions taken by all the involved stakeholders in response to the disclosure of potential vulnerabilities in medical devices and summarize the positions of major societies in response to these events....
We outline the actions taken by all the involved stakeholders in response to the disclosure of potential vulnerabilities in medical devices …
Puberty and depression.
Angold A, Costello EJ. Angold A, et al. Child Adolesc Psychiatr Clin N Am. 2006 Oct;15(4):919-37, ix. doi: 10.1016/j.chc.2006.05.013. Child Adolesc Psychiatr Clin N Am. 2006. PMID: 16952768 Review.
Immunogenetics and genomics.
Hill AV. Hill AV. Lancet. 2001 Jun 23;357(9273):2037-41. doi: 10.1016/S0140-6736(00)05117-5. Lancet. 2001. PMID: 11438157 Review.
Genetic linkage analysis of multicase families has recently identified new major susceptibility loci for a few immunologically determined common diseases. ...
Genetic linkage analysis of multicase families has recently identified new major susceptibility loci for a few immunologically determ …
617 results