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Page 1
Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity.
Ghallab A, Hassan R, Hofmann U, Friebel A, Hobloss Z, Brackhagen L, Begher-Tibbe B, Myllys M, Reinders J, Overbeck N, Sezgin S, Zühlke S, Seddek AL, Murad W, Brecklinghaus T, Kappenberg F, Rahnenführer J, González D, Goldring C, Copple IM, Marchan R, Longerich T, Vucur M, Luedde T, Urban S, Canbay A, Schreiter T, Trauner M, Akakpo JY, Olyaee M, Curry SC, Sowa JP, Jaeschke H, Hoehme S, Hengstler JG. Ghallab A, et al. Among authors: friebel a. J Hepatol. 2022 Jul;77(1):71-83. doi: 10.1016/j.jhep.2022.01.020. Epub 2022 Feb 5. J Hepatol. 2022. PMID: 35131407 Free PMC article.
Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis.
Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek AL, Abbas T, Abdelmageed N, Morad SAF, Morad W, Hamdy A, Albrecht W, Kittana N, Assali M, Vartak N, van Thriel C, Sous A, Nell P, Villar-Fernandez M, Cadenas C, Genc E, Marchan R, Luedde T, Åkerblad P, Mattsson J, Marschall HU, Hoehme S, Stirnimann G, Schwab M, Boor P, Amann K, Schmitz J, Bräsen JH, Rahnenführer J, Edlund K, Karpen SJ, Simbrunner B, Reiberger T, Mandorfer M, Trauner M, Dawson PA, Lindström E, Hengstler JG. Ghallab A, et al. Among authors: friebel a. J Hepatol. 2024 Feb;80(2):268-281. doi: 10.1016/j.jhep.2023.10.035. Epub 2023 Nov 7. J Hepatol. 2024. PMID: 37939855 Free PMC article.
Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A.
Hassan R, González D, Hobloss Z, Brackhagen L, Myllys M, Friebel A, Seddek AL, Marchan R, Cramer B, Humpf HU, Hoehme S, Degen GH, Hengstler JG, Ghallab A. Hassan R, et al. Among authors: friebel a. Arch Toxicol. 2022 Dec;96(12):3349-3361. doi: 10.1007/s00204-022-03395-y. Epub 2022 Oct 13. Arch Toxicol. 2022. PMID: 36227364 Free PMC article.
Cognitive Functions, Neurotransmitter Alterations, and Hippocampal Microstructural Changes in Mice Caused by Feeding on Western Diet.
Custodio RJP, Hobloss Z, Myllys M, Hassan R, González D, Reinders J, Bornhorst J, Weishaupt AK, Seddek AL, Abbas T, Friebel A, Hoehme S, Getzmann S, Hengstler JG, van Thriel C, Ghallab A. Custodio RJP, et al. Among authors: friebel a. Cells. 2023 Sep 21;12(18):2331. doi: 10.3390/cells12182331. Cells. 2023. PMID: 37759553 Free PMC article.
Acetaminophen overdose causes a breach of the blood-bile barrier in mice but not in rats.
Hassan R, Hobloss Z, Myllys M, González D, Begher-Tibbe B, Reinders J, Friebel A, Hoehme S, Abdelmageed N, Abbas AA, Seddek AL, Morad SAF, Hengstler JG, Ghallab A. Hassan R, et al. Among authors: friebel a. Arch Toxicol. 2024 May;98(5):1533-1542. doi: 10.1007/s00204-024-03705-6. Epub 2024 Mar 11. Arch Toxicol. 2024. PMID: 38466352
Intravital Dynamic and Correlative Imaging of Mouse Livers Reveals Diffusion-Dominated Canalicular and Flow-Augmented Ductular Bile Flux.
Vartak N, Guenther G, Joly F, Damle-Vartak A, Wibbelt G, Fickel J, Jörs S, Begher-Tibbe B, Friebel A, Wansing K, Ghallab A, Rosselin M, Boissier N, Vignon-Clementel I, Hedberg C, Geisler F, Hofer H, Jansen P, Hoehme S, Drasdo D, Hengstler JG. Vartak N, et al. Among authors: friebel a. Hepatology. 2021 Apr;73(4):1531-1550. doi: 10.1002/hep.31422. Epub 2021 Mar 16. Hepatology. 2021. PMID: 32558958 Free article.
Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity.
Hassan R, Friebel A, Brackhagen L, Hobloss Z, Myllys M, González D, Albrecht W, Mohammed ESI, Seddek AL, Marchan R, Cadenas C, Cramer B, Humpf HU, Hartl L, Simbrunner B, Reiberger T, Trauner M, Hoehme S, Degen GH, Hengstler JG, Ghallab A. Hassan R, et al. Among authors: friebel a. Arch Toxicol. 2022 Nov;96(11):2967-2981. doi: 10.1007/s00204-022-03361-8. Epub 2022 Aug 13. Arch Toxicol. 2022. PMID: 35962801 Free PMC article.
17 results