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HIV integration in the human brain is linked to microglial activation and 3D genome remodeling.
Plaza-Jennings AL, Valada A, O'Shea C, Iskhakova M, Hu B, Javidfar B, Ben Hutta G, Lambert TY, Murray J, Kassim B, Chandrasekaran S, Chen BK, Morgello S, Won H, Akbarian S. Plaza-Jennings AL, et al. Among authors: valada a. Mol Cell. 2022 Dec 15;82(24):4647-4663.e8. doi: 10.1016/j.molcel.2022.11.016. Mol Cell. 2022. PMID: 36525955 Free PMC article.
3D Genome Plasticity in Normal and Diseased Neurodevelopment.
Plaza-Jennings A, Valada A, Akbarian S. Plaza-Jennings A, et al. Among authors: valada a. Genes (Basel). 2022 Nov 1;13(11):1999. doi: 10.3390/genes13111999. Genes (Basel). 2022. PMID: 36360237 Free PMC article. Review.
Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk.
Powell SK, O'Shea C, Townsley K, Prytkova I, Dobrindt K, Elahi R, Iskhakova M, Lambert T, Valada A, Liao W, Ho SM, Slesinger PA, Huckins LM, Akbarian S, Brennand KJ. Powell SK, et al. Among authors: valada a. Mol Psychiatry. 2023 May;28(5):1970-1982. doi: 10.1038/s41380-021-01273-0. Epub 2021 Sep 7. Mol Psychiatry. 2023. PMID: 34493831 Free PMC article.
Single Nucleus Transcriptomics Reveals Pervasive Glial Activation in Opioid Overdose Cases.
Wei J, Lambert TY, Valada A, Patel N, Walker K, Lenders J, Schmidt CJ, Iskhakova M, Alazizi A, Mair-Meijers H, Mash DC, Luca F, Pique-Regi R, Bannon MJ, Akbarian S. Wei J, et al. Among authors: valada a. bioRxiv [Preprint]. 2023 Mar 9:2023.03.07.531400. doi: 10.1101/2023.03.07.531400. bioRxiv. 2023. PMID: 36945611 Free PMC article. Preprint.