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Showing results for adam beta
Your search for Adam Běťák retrieved no results
A double blind, placebo-controlled randomized comparative study on the efficacy of phytosterol-enriched and conventional saw palmetto oil in mitigating benign prostate hyperplasia and androgen deficiency.
Sudeep HV, Thomas JV, Shyamprasad K. Sudeep HV, et al. BMC Urol. 2020 Jul 3;20(1):86. doi: 10.1186/s12894-020-00648-9. BMC Urol. 2020. PMID: 32620155 Free PMC article. Clinical Trial.
BACKGROUND: The present clinical trial was conducted to evaluate the efficacy and tolerability of a standardized saw palmetto oil containing 3% beta-sitosterol in the treatment of benign prostate hyperplasia (BPH) and androgen deficiency. ...During the trial, the androgen …
BACKGROUND: The present clinical trial was conducted to evaluate the efficacy and tolerability of a standardized saw palmetto oil containing …
Epigenetic Regulation of a Disintegrin and Metalloproteinase (ADAM) Transcription in Colorectal Cancer Cells: Involvement of beta-Catenin, BRG1, and KDM4.
Sun L, Chen B, Wu J, Jiang C, Fan Z, Feng Y, Xu Y. Sun L, et al. Front Cell Dev Biol. 2020 Sep 11;8:581692. doi: 10.3389/fcell.2020.581692. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33043016 Free PMC article.
Overexpression of ADAM10/17/19 in HCT116 cells enhanced, whereas depletion of ADAM10/17/19 in SW480 cells weakened, migration and invasion. ADAM expression was activated by the Wnt signaling pathway, which could be attributed to direct binding of beta-catenin on the …
Overexpression of ADAM10/17/19 in HCT116 cells enhanced, whereas depletion of ADAM10/17/19 in SW480 cells weakened, migration and invasion. …
Meprin beta induces activities of A disintegrin and metalloproteinases 9, 10, and 17 by specific prodomain cleavage.
Wichert R, Scharfenberg F, Colmorgen C, Koudelka T, Schwarz J, Wetzel S, Potempa B, Potempa J, Bartsch JW, Sagi I, Tholey A, Saftig P, Rose-John S, Becker-Pauly C. Wichert R, et al. FASEB J. 2019 Nov;33(11):11925-11940. doi: 10.1096/fj.201801371R. Epub 2019 Aug 9. FASEB J. 2019. PMID: 31381863 Free PMC article.
Because ADAM prodomains can act as specific inhibitors, we postulate a role for meprin beta in the regulation of ADAM activities. ...Direct interaction of meprin beta and ADAM proteases could be shown by immunofluorescence microscopy and immunop …
Because ADAM prodomains can act as specific inhibitors, we postulate a role for meprin beta in the regulation of ADAM a …
Meprin and ADAM proteases as triggers of systemic inflammation in sepsis.
Rahn S, Becker-Pauly C. Rahn S, et al. FEBS Lett. 2022 Mar;596(5):534-556. doi: 10.1002/1873-3468.14225. Epub 2021 Nov 18. FEBS Lett. 2022. PMID: 34762736 Free article. Review.
Protease-mediated ectodomain shedding of cytokines and their receptors represents a central mechanism in the regulation of inflammatory responses. The metalloprotease A disintegrin and metalloproteinase (ADAM) 17 is the best-characterized ectodomain sheddase capable of rel …
Protease-mediated ectodomain shedding of cytokines and their receptors represents a central mechanism in the regulation of inflammatory resp …
Shedding light on ADAM metalloproteinases.
Huovila AP, Turner AJ, Pelto-Huikko M, Kärkkäinen I, Ortiz RM. Huovila AP, et al. Trends Biochem Sci. 2005 Jul;30(7):413-22. doi: 10.1016/j.tibs.2005.05.006. Trends Biochem Sci. 2005. PMID: 15949939 Review.
Recent gene-manipulation studies have established the role of ADAM-mediated shedding in mammalian physiology and, in addition, raised the issue of functional redundancy among ADAM sheddases. ADAM sheddases activate, for example, growth factors and cytokines, …
Recent gene-manipulation studies have established the role of ADAM-mediated shedding in mammalian physiology and, in addition, raised …
Removal of extracellular human amyloid beta aggregates by extracellular proteases in C. elegans.
Jongsma E, Goyala A, Mateos JM, Ewald CY. Jongsma E, et al. Elife. 2023 Sep 20;12:e83465. doi: 10.7554/eLife.83465. Elife. 2023. PMID: 37728486 Free PMC article.
The amyloid beta (Abeta) plaques found in Alzheimer's disease (AD) patients' brains contain collagens and are embedded extracellularly. ...
The amyloid beta (Abeta) plaques found in Alzheimer's disease (AD) patients' brains contain collagens and are embedded extracellularl …
Beta-lactam/beta-lactamase inhibitor combinations in empiric management of pediatric infections.
Adam D. Adam D. J Int Med Res. 2002;30 Suppl 1:10A-19A. doi: 10.1177/14732300020300S103. J Int Med Res. 2002. PMID: 11921490 Free article. Review.
Beta-lactam antibiotics have long played a central role in the management of pediatric infections. However, widespread beta-lactam resistance among community- and hospital-acquired pathogens, mainly due to beta-lactamase production, has reduced the usefulness …
Beta-lactam antibiotics have long played a central role in the management of pediatric infections. However, widespread beta-la …
Fertilin beta and other ADAMs as integrin ligands: insights into cell adhesion and fertilization.
Evans JP. Evans JP. Bioessays. 2001 Jul;23(7):628-39. doi: 10.1002/bies.1088. Bioessays. 2001. PMID: 11462216 Review.
Fertilin beta (also known as ADAM2) participates in sperm-egg membrane binding, and it has long been hypothesized that this function is achieved through the interaction of the disintegrin domain of fertilin beta with an integrin on the egg surface. There are now app …
Fertilin beta (also known as ADAM2) participates in sperm-egg membrane binding, and it has long been hypothesized that this function …
Human fertilin beta: identification, characterization, and chromosomal mapping of an ADAM gene family member.
Vidaeus CM, von Kapp-Herr C, Golden WL, Eddy RL, Shows TB, Herr JC. Vidaeus CM, et al. Mol Reprod Dev. 1997 Mar;46(3):363-9. doi: 10.1002/(SICI)1098-2795(199703)46:3<363::AID-MRD15>3.0.CO;2-#. Mol Reprod Dev. 1997. PMID: 9041139
Due to this domain organization, human fertilin beta has been identified as a member of the ADAM family, which is composed of membrane-anchored proteins having A Disintegrin And Metalloprotease domain. The amino acid sequence of human fertilin beta shares 90% …
Due to this domain organization, human fertilin beta has been identified as a member of the ADAM family, which is composed of …
The Role of ADAM10 in Alzheimer's Disease.
Yuan XZ, Sun S, Tan CC, Yu JT, Tan L. Yuan XZ, et al. J Alzheimers Dis. 2017;58(2):303-322. doi: 10.3233/JAD-170061. J Alzheimers Dis. 2017. PMID: 28409746 Review.
As a member of the A Disintegrin And Metalloproteinase (ADAM) family, ADAM10 has been identified as the constitutive alpha-secretase in the process of amyloid-beta protein precursor (AbetaPP) cleavage and plays a critical role in reducing the generation of the amylo …
As a member of the A Disintegrin And Metalloproteinase (ADAM) family, ADAM10 has been identified as the constitutive alpha-secretase …
2,209 results