Use of anti-neoepitope antibodies for the analysis of degradative events in cartilage and the molecular basis for neoepitope specificity.
Mort JS, Flannery CR, Makkerh J, Krupa JC, Lee ER.
Mort JS, et al.
Biochem Soc Symp. 2003;(70):107-14. doi: 10.1042/bss0700107.
Biochem Soc Symp. 2003.
PMID: 14587286
Review.
Using the newborn rat long bone as a model system, it was shown that the active form of ADAMTS-4 [ADAM (a disintegrin and metalloproteinase) with thrombospondin motifs-4], but not ADAMTS-5, co-localizes with the aggrecan cleavage neoepitopes known to be produced by this me …
Using the newborn rat long bone as a model system, it was shown that the active form of ADAMTS-4 [ADAM (a disintegrin and metalloprot …