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Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2.
Gaynor KU, Vaysburd M, Harman MAJ, Albecka A, Jeffrey P, Beswick P, Papa G, Chen L, Mallery D, McGuinness B, Van Rietschoten K, Stanway S, Brear P, Lulla A, Ciazynska K, Chang VT, Sharp J, Neary M, Box H, Herriott J, Kijak E, Tatham L, Bentley EG, Sharma P, Kirby A, Han X, Stewart JP, Owen A, Briggs JAG, Hyvönen M, Skynner MJ, James LC. Gaynor KU, et al. Among authors: kirby a. Nat Commun. 2023 Jun 16;14(1):3583. doi: 10.1038/s41467-023-39158-1. Nat Commun. 2023. PMID: 37328472 Free PMC article.
Neuroinvasion and Neurotropism by SARS-CoV-2 Variants in the K18-hACE2 Mouse.
Seehusen F, Clark JJ, Sharma P, Bentley EG, Kirby A, Subramaniam K, Wunderlin-Giuliani S, Hughes GL, Patterson EI, Michael BD, Owen A, Hiscox JA, Stewart JP, Kipar A. Seehusen F, et al. Among authors: kirby a. Viruses. 2022 May 11;14(5):1020. doi: 10.3390/v14051020. Viruses. 2022. PMID: 35632761 Free PMC article.
Hypoxia inducible factors inhibit respiratory syncytial virus infection by modulation of nucleolin expression.
Zhuang X, Gallo G, Sharma P, Ha J, Magri A, Borrmann H, Harris JM, Tsukuda S, Bentley E, Kirby A, de Neck S, Yang H, Balfe P, Wing PAC, Matthews D, Harris AL, Kipar A, Stewart JP, Bailey D, McKeating JA. Zhuang X, et al. Among authors: kirby a. iScience. 2023 Dec 18;27(1):108763. doi: 10.1016/j.isci.2023.108763. eCollection 2024 Jan 19. iScience. 2023. PMID: 38261926 Free PMC article.
Pharmacodynamics of the Novel Metallo-β-Lactamase Inhibitor ANT2681 in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae.
Das S, Johnson A, McEntee L, Farrington N, Kirby A, Unsworth J, Jimenez-Valverde A, Kolamunnage-Dona R, Bousquet J, Alibaud L, Sable C, Zalacain M, Everett M, Hope W. Das S, et al. Among authors: kirby a. Antimicrob Agents Chemother. 2020 Oct 20;64(11):e01076-20. doi: 10.1128/AAC.01076-20. Print 2020 Oct 20. Antimicrob Agents Chemother. 2020. PMID: 32778549 Free PMC article.
11 results