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Synthetic 5-amino-6-D-ribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivo.
Nelson AG, Wang H, Dewar PM, Eddy EM, Li S, Lim XY, Patton T, Zhou Y, Pediongco TJ, Meehan LJ, Meehan BS, Mak JYW, Fairlie DP, Stent AW, Kjer-Nielsen L, McCluskey J, Eckle SBG, Corbett AJ, Souter MNT, Chen Z. Nelson AG, et al. Front Immunol. 2023 Aug 31;14:1109759. doi: 10.3389/fimmu.2023.1109759. eCollection 2023. Front Immunol. 2023. PMID: 37720229 Free PMC article.
RIPK3 controls MAIT cell accumulation during development but not during infection.
Patton T, Zhao Z, Lim XY, Eddy E, Wang H, Nelson AG, Ennis B, Eckle SBG, Souter MNT, Pediongco TJ, Koay HF, Zhang JG, Djajawi TM, Louis C, Lalaoui N, Jacquelot N, Lew AM, Pellicci DG, McCluskey J, Zhan Y, Chen Z, Lawlor KE, Corbett AJ. Patton T, et al. Among authors: nelson ag. Cell Death Dis. 2023 Feb 11;14(2):111. doi: 10.1038/s41419-023-05619-0. Cell Death Dis. 2023. PMID: 36774342 Free PMC article.
The balance of interleukin-12 and interleukin-23 determines the bias of MAIT1 versus MAIT17 responses during bacterial infection.
Wang H, Nelson AG, Wang B, Zhao Z, Lim XY, Shi M, Meehan LJ, Jia X, Kedzierska K, Meehan BS, Eckle SB, Souter MN, Pediongco TJ, Mak JY, Fairlie DP, McCluskey J, Wang Z, Corbett AJ, Chen Z. Wang H, et al. Among authors: nelson ag. Immunol Cell Biol. 2022 Aug;100(7):547-561. doi: 10.1111/imcb.12556. Epub 2022 Jun 2. Immunol Cell Biol. 2022. PMID: 35514192 Free PMC article.
Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection.
Zhao Z, Wang H, Shi M, Zhu T, Pediongco T, Lim XY, Meehan BS, Nelson AG, Fairlie DP, Mak JYW, Eckle SBG, de Lima Moreira M, Tumpach C, Bramhall M, Williams CG, Lee HJ, Haque A, Evrard M, Rossjohn J, McCluskey J, Corbett AJ, Chen Z. Zhao Z, et al. Among authors: nelson ag. Nat Commun. 2021 Jul 16;12(1):4355. doi: 10.1038/s41467-021-24570-2. Nat Commun. 2021. PMID: 34272362 Free PMC article.