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Discovery and Optimization of Potent and Orally Available CTP Synthetase Inhibitors for Use in Treatment of Diseases Driven by Aberrant Immune Cell Proliferation.
Novak A, Laughton D, Lane R, Blackham E, Thomas J, Chatzopoulou E, Wrigglesworth J, Quddus A, Ahmed S, Cousin D, Duffy L, Dubois N, Unitt J, Orban K, Browne E, Ward M, Mycock D, Ieva M, Bland N, George P, Bourne T, Asnagli H, Birch L, Jones G. Novak A, et al. Among authors: quddus a. J Med Chem. 2022 Dec 22;65(24):16640-16650. doi: 10.1021/acs.jmedchem.2c01446. Epub 2022 Nov 30. J Med Chem. 2022. PMID: 36449304
Expedient synthesis of an atypical oxazolidinone compound library.
Cully SJ, Storr TE, Rawling MJ, Abeysena IR, Hamza D, Jones G, Pearce CA, Quddus A, Lewis W, Stockman RA. Cully SJ, et al. Among authors: quddus a. Bioorg Med Chem. 2016 Nov 1;24(21):5249-5257. doi: 10.1016/j.bmc.2016.08.046. Epub 2016 Aug 27. Bioorg Med Chem. 2016. PMID: 27622748
Intra-operative Tranexamic Acid Administration Significantly Decreases Incidence of Postoperative Bleeding Without Increasing Venous Thromboembolism Risk After Laparoscopic Sleeve Gastrectomy: a Retrospective Cohort Study of Over 400 Patients.
Hossain N, Kaur V, Mahran M, Quddus A, Mukhopadhyay S, Shah A, Agrawal S. Hossain N, et al. Among authors: quddus a. Obes Surg. 2024 Feb;34(2):396-401. doi: 10.1007/s11695-023-07021-3. Epub 2024 Jan 3. Obes Surg. 2024. PMID: 38168716
11 results