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Large-scale validation of skin prion seeding activity as a biomarker for diagnosis of prion diseases.
Zhang W, Orrú CD, Foutz A, Ding M, Yuan J, Shah SZA, Zhang J, Kotobelli K, Gerasimenko M, Gilliland T, Chen W, Tang M, Cohen M, Safar J, Xu B, Hong DJ, Cui L, Hughson AG, Schonberger LB, Tatsuoka C, Chen SG, Greenlee JJ, Wang Z, Appleby BS, Caughey B, Zou WQ. Zhang W, et al. Among authors: foutz a. Acta Neuropathol. 2024 Jan 17;147(1):17. doi: 10.1007/s00401-023-02661-2. Acta Neuropathol. 2024. PMID: 38231266
Diagnosis of prion diseases by RT-QuIC results in improved surveillance.
Rhoads DD, Wrona A, Foutz A, Blevins J, Glisic K, Person M, Maddox RA, Belay ED, Schonberger LB, Tatsuoka C, Cohen ML, Appleby BS. Rhoads DD, et al. Among authors: foutz a. Neurology. 2020 Aug 25;95(8):e1017-e1026. doi: 10.1212/WNL.0000000000010086. Epub 2020 Jun 22. Neurology. 2020. PMID: 32571851
Early preclinical detection of prions in the skin of prion-infected animals.
Wang Z, Manca M, Foutz A, Camacho MV, Raymond GJ, Race B, Orru CD, Yuan J, Shen P, Li B, Lang Y, Dang J, Adornato A, Williams K, Maurer NR, Gambetti P, Xu B, Surewicz W, Petersen RB, Dong X, Appleby BS, Caughey B, Cui L, Kong Q, Zou WQ. Wang Z, et al. Among authors: foutz a. Nat Commun. 2019 Jan 16;10(1):247. doi: 10.1038/s41467-018-08130-9. Nat Commun. 2019. PMID: 30651538 Free PMC article.
Ring trial of 2nd generation RT-QuIC diagnostic tests for sporadic CJD.
Orrú CD, Groveman BR, Foutz A, Bongianni M, Cardone F, McKenzie N, Culeux A, Poleggi A, Grznarova K, Perra D, Fiorini M, Liu X, Ladogana A, Sbriccoli M, Hughson AG, Haïk S, Green AJ, Geschwind MD, Pocchiari M, Safar JG, Zanusso G, Caughey B. Orrú CD, et al. Among authors: foutz a. Ann Clin Transl Neurol. 2020 Nov;7(11):2262-2271. doi: 10.1002/acn3.51219. Ann Clin Transl Neurol. 2020. PMID: 33185334 Free PMC article. Clinical Trial.
Publisher Correction: Early preclinical detection of prions in the skin of prion-infected animals.
Wang Z, Manca M, Foutz A, Camacho MV, Raymond GJ, Race B, Orru CD, Yuan J, Shen P, Li B, Lang Y, Dang J, Adornato A, Williams K, Maurer NR, Gambetti P, Xu B, Surewicz W, Petersen RB, Dong X, Appleby BS, Caughey B, Cui L, Kong Q, Zou WQ. Wang Z, et al. Among authors: foutz a. Nat Commun. 2019 Feb 4;10(1):640. doi: 10.1038/s41467-019-08648-6. Nat Commun. 2019. PMID: 30718499 Free PMC article.
Diagnostic and prognostic value of human prion detection in cerebrospinal fluid.
Foutz A, Appleby BS, Hamlin C, Liu X, Yang S, Cohen Y, Chen W, Blevins J, Fausett C, Wang H, Gambetti P, Zhang S, Hughson A, Tatsuoka C, Schonberger LB, Cohen ML, Caughey B, Safar JG. Foutz A, et al. Ann Neurol. 2017 Jan;81(1):79-92. doi: 10.1002/ana.24833. Ann Neurol. 2017. PMID: 27893164 Free PMC article.
Decrease in Skin Prion-Seeding Activity of Prion-Infected Mice Treated with a Compound Against Human and Animal Prions: a First Possible Biomarker for Prion Therapeutics.
Ding M, Teruya K, Zhang W, Lee HW, Yuan J, Oguma A, Foutz A, Camacho MV, Mitchell M, Greenlee JJ, Kong Q, Doh-Ura K, Cui L, Zou WQ. Ding M, et al. Among authors: foutz a. Mol Neurobiol. 2021 Sep;58(9):4280-4292. doi: 10.1007/s12035-021-02418-6. Epub 2021 May 13. Mol Neurobiol. 2021. PMID: 33983547 Free PMC article.