Aarajana Shrestha - Search Results

Year	Number of Results
2015	3
2016	4
2017	8
2018	6
2019	4
2020	1
2021	6
2022	2
2023	1
2024	0

1

Targeting Peroxisome Proliferator-Activated Receptor Delta (PPARδ): A Medicinal Chemistry Perspective.

Kadayat TM, Shrestha A, Jeon YH, An H, Kim J, Cho SJ, Chin J. Kadayat TM, et al. Among authors: shrestha a. J Med Chem. 2020 Sep 24;63(18):10109-10134. doi: 10.1021/acs.jmedchem.9b01882. Epub 2020 Jul 28. J Med Chem. 2020. PMID: 32539376 Review.

2

Targeting the Nuclear Receptor-Binding SET Domain Family of Histone Lysine Methyltransferases for Cancer Therapy: Recent Progress and Perspectives.

Shrestha A, Kim N, Lee SJ, Jeon YH, Song JJ, An H, Cho SJ, Kadayat TM, Chin J. Shrestha A, et al. J Med Chem. 2021 Oct 28;64(20):14913-14929. doi: 10.1021/acs.jmedchem.1c01116. Epub 2021 Sep 7. J Med Chem. 2021. PMID: 34488340 Review.

3

Potent inhibitory activity of hydroxylated 2-benzylidene-3,4-dihydronaphthalen-1(2H)-ones on LPS-stimulated reactive oxygen species production in RAW 264.7 macrophages.

Kunwar S, Min Lee S, Man Kadayat T, Shrestha A, Park PH, Lee ES. Kunwar S, et al. Among authors: shrestha a. Bioorg Med Chem Lett. 2022 Oct 1;73:128921. doi: 10.1016/j.bmcl.2022.128921. Epub 2022 Aug 3. Bioorg Med Chem Lett. 2022. PMID: 35932905

4

Di-indenopyridines as topoisomerase II-selective anticancer agents: Design, synthesis, and structure-activity relationships.

Shrestha A, Hwang SY, Kunwar S, Man Kadayat T, Park S, Liu Y, Jo H, Sheen N, Seo M, Lee ES, Kwon Y. Shrestha A, et al. Bioorg Med Chem. 2023 Aug 15;91:117403. doi: 10.1016/j.bmc.2023.117403. Epub 2023 Jul 4. Bioorg Med Chem. 2023. PMID: 37418826

5

Synthesis and structure-activity relationships of hydroxylated and halogenated 2,4-diaryl benzofuro[3,2-b]pyridin-7-ols as selective topoisomerase IIα inhibitors.

Thapa Magar TB, Hee Seo S, Shrestha A, Kim JA, Kunwar S, Bist G, Kwon Y, Lee ES. Thapa Magar TB, et al. Among authors: shrestha a. Bioorg Chem. 2021 Jun;111:104884. doi: 10.1016/j.bioorg.2021.104884. Epub 2021 Apr 1. Bioorg Chem. 2021. PMID: 33872925

6

Antioxidative and anti-inflammatory activity of psiguadial B and its halogenated analogues as potential neuroprotective agents.

Man Kadayat T, Eun Kim D, Bong Lee S, Jung K, Eun Park S, Hong JY, Kim J, Shrestha A, Kim DS, An H, Kim N, Lee SJ, Kwon S, Kim S, Yeon Hwang J, Kim S, Hahn D, Choi H, Nam SJ, Hyun Jeon Y, Jin Hwang J, Jin Cho S, Chin J. Man Kadayat T, et al. Among authors: shrestha a. Bioorg Chem. 2021 Aug;113:105027. doi: 10.1016/j.bioorg.2021.105027. Epub 2021 May 26. Bioorg Chem. 2021. PMID: 34098398

7

Identification of sulfonyl-loxoprofen as novel phase 2 conjugate in rat.

Shrestha R, Paudel S, Cho P, Shrestha A, Jeong TC, Lee ES, Lee T, Lee S. Shrestha R, et al. Among authors: shrestha a. Biopharm Drug Dispos. 2019 Jul;40(7):234-241. doi: 10.1002/bdd.2196. Epub 2019 Jul 19. Biopharm Drug Dispos. 2019. PMID: 31242324

8

Novel 2-aryl-4-(4'-hydroxyphenyl)-5H-indeno[1,2-b]pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors.

Park S, Kadayat TM, Jun KY, Thapa Magar TB, Bist G, Shrestha A, Lee ES, Kwon Y. Park S, et al. Among authors: shrestha a. Eur J Med Chem. 2017 Jan 5;125:14-28. doi: 10.1016/j.ejmech.2016.09.019. Epub 2016 Sep 8. Eur J Med Chem. 2017. PMID: 27643560

9

Identification of new halogen-containing 2,4-diphenyl indenopyridin-5-one derivative as a boosting agent for the anticancer responses of clinically available topoisomerase inhibitors.

Hwang SY, Shrestha A, Park S, Bist G, Kunwar S, Kadayat TM, Jang H, Seo M, Sheen N, Kim S, Jeon KH, Lee ES, Kwon Y. Hwang SY, et al. Among authors: shrestha a. Eur J Med Chem. 2022 Jan 5;227:113916. doi: 10.1016/j.ejmech.2021.113916. Epub 2021 Oct 11. Eur J Med Chem. 2022. PMID: 34678573

10

2-Chlorophenyl-substituted benzofuro[3,2-b]pyridines with enhanced topoisomerase inhibitory activity: The role of the chlorine substituent.

Thapa Magar TB, Kadayat TM, Lee HJ, Park S, Bist G, Shrestha A, Kwon Y, Lee ES. Thapa Magar TB, et al. Among authors: shrestha a. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3279-3283. doi: 10.1016/j.bmcl.2017.06.025. Epub 2017 Jun 9. Bioorg Med Chem Lett. 2017. PMID: 28633898

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