ONECUT2 is a driver of neuroendocrine prostate cancer.
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Nat Commun. 2019 Jan 17;10(1):278. doi: 10.1038/s41467-018-08133-6.
Nat Commun. 2019.
PMID: 30655535
Free PMC article.
Neuroendocrine prostate cancer (NEPC), a lethal form of the disease, is characterized by loss of androgen receptor (AR) signaling during neuroendocrine transdifferentiation, which results in resistance to AR-targeted therapy. Clinically, genomically and epigenetically, NEP …
Neuroendocrine prostate cancer (NEPC), a lethal form of the disease, is characterized by loss of androgen receptor (AR) signaling dur …