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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1866 1
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1874 2
1881 1
1895 1
1929 1
1931 2
1939 1
1942 1
1945 3
1947 1
1948 14
1949 11
1950 8
1951 4
1952 11
1953 7
1954 5
1955 5
1956 6
1957 11
1958 17
1959 11
1960 11
1961 11
1962 36
1963 37
1964 49
1965 57
1966 38
1967 47
1968 34
1969 51
1970 78
1971 93
1972 111
1973 116
1974 116
1975 172
1976 186
1977 194
1978 195
1979 242
1980 275
1981 251
1982 253
1983 295
1984 328
1985 370
1986 418
1987 461
1988 555
1989 589
1990 581
1991 592
1992 676
1993 734
1994 792
1995 913
1996 1055
1997 1055
1998 1101
1999 1326
2000 1525
2001 1751
2002 1919
2003 2112
2004 2281
2005 2656
2006 2881
2007 3269
2008 5044
2009 5988
2010 6470
2011 6923
2012 7059
2013 6174
2014 6178
2015 6603
2016 6238
2017 6933
2018 7647
2019 8600
2020 10513
2021 11903
2022 11746
2023 11072
2024 5069

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The following term was not found in PubMed: Hiipoi
Page 1
Heme Oxygenase-1: An Anti-Inflammatory Effector in Cardiovascular, Lung, and Related Metabolic Disorders.
Ryter SW. Ryter SW. Antioxidants (Basel). 2022 Mar 15;11(3):555. doi: 10.3390/antiox11030555. Antioxidants (Basel). 2022. PMID: 35326205 Free PMC article. Review.
HO activity is represented by two distinct isozymes, the inducible form, HO-1, and a constitutive form, HO-2, encoded by distinct genes (HMOX1, HMOX2, respectively). ...Strategies targeting the HO-1 pathway, including genetic or chemical modulation of …
HO activity is represented by two distinct isozymes, the inducible form, HO-1, and a constitutive form, HO-2, encoded b …
Heme-Oxygenase-1.
Facchinetti MM. Facchinetti MM. Antioxid Redox Signal. 2020 Jun 10;32(17):1239-1242. doi: 10.1089/ars.2020.8065. Antioxid Redox Signal. 2020. PMID: 32148070
This Forum issue "Heme Oxygenase" (HO) includes original research articles and reviews that are aimed at understanding the role of HO-1 in several pathophysiological conditions, specially addressing those involving inflammation and oxidative damage. ...Contrariwise, …
This Forum issue "Heme Oxygenase" (HO) includes original research articles and reviews that are aimed at understanding the role of …
A focus on heme oxygenase-1 (HO-1) inhibitors.
Pittalà V, Salerno L, Romeo G, Modica MN, Siracusa MA. Pittalà V, et al. Curr Med Chem. 2013;20(30):3711-32. doi: 10.2174/0929867311320300003. Curr Med Chem. 2013. PMID: 23746277 Review.
HO exists in two distinct, catalytically active isoforms: HO-1 and HO-2. HO-1 is an inducible 32-kDa protein, while HO-2 is a constitutively synthesized 36-kDa protein and generally is unresponsive to any of the inducers of HO-1. ...
HO exists in two distinct, catalytically active isoforms: HO-1 and HO-2. HO-1 is an inducible 32-kDa protein, wh …
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors.
Intagliata S, Salerno L, Ciaffaglione V, Leonardi C, Fallica AN, Carota G, Amata E, Marrazzo A, Pittalà V, Romeo G. Intagliata S, et al. Eur J Med Chem. 2019 Dec 1;183:111703. doi: 10.1016/j.ejmech.2019.111703. Epub 2019 Sep 17. Eur J Med Chem. 2019. PMID: 31550661 Review.
Among the different HO isoforms, HO-2 stands out for its neuroprotective properties and modulatory activity in male reproduction. ...To the best of our knowledge, among HO-2 inhibitors, clemizole derivatives are the most selective HO-2 inhibitors repor …
Among the different HO isoforms, HO-2 stands out for its neuroprotective properties and modulatory activity in male reproducti …
HO-1: a new marker for predicting postoperative recurrence of CRSwNP.
Gong MJ, Wang YS, Lou M, Ma RP, Hu ZZ, Zheng GX, Zhang Y. Gong MJ, et al. Acta Otolaryngol. 2023 Feb;143(2):170-175. doi: 10.1080/00016489.2023.2168054. Epub 2023 Jan 27. Acta Otolaryngol. 2023. PMID: 36705254
We use Immunohistochemical staining to determine the expression of HO-1 in tissues. We use Spearman correlation test to analyze the correlation between HO-1 positive cell count and clinical score, and ROC curve to assess the value of HO-1 positive cell count …
We use Immunohistochemical staining to determine the expression of HO-1 in tissues. We use Spearman correlation test to analyze the c …
HO-1 overexpression and underexpression: Clinical implications.
Drummond GS, Baum J, Greenberg M, Lewis D, Abraham NG. Drummond GS, et al. Arch Biochem Biophys. 2019 Sep 30;673:108073. doi: 10.1016/j.abb.2019.108073. Epub 2019 Aug 16. Arch Biochem Biophys. 2019. PMID: 31425676 Free PMC article. Review.
In this review we examine the effects of both over- and under-production of heme oxygenase-1 (HO-1) and HO activity on a broad spectrum of biological systems and on vascular disease. In a few instances e.g., neonatal jaundice, overproduction of HO-1 and incre …
In this review we examine the effects of both over- and under-production of heme oxygenase-1 (HO-1) and HO activity on a broad …
N-(3-Nitro-phen-yl)maleamic acid.
Gowda BT, Tokarčík M, Shakuntala K, Kožíšek J, Fuess H. Gowda BT, et al. Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 16;66(Pt 7):o1671-2. doi: 10.1107/S1600536810022245. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21587897 Free PMC article.
The mol-ecular structure is stabilized by two intra-molecular hydrogen bonds. The first is a short O-HO hydrogen bond (HO distance = 1.57 A) within the maleamic acid unit and the second is a C-HO hydrogen bond (HO distance = 2.24 A) which connects the …
The mol-ecular structure is stabilized by two intra-molecular hydrogen bonds. The first is a short O-HO hydrogen bond (HO dist …
Antiapoptotic role of heme oxygenase (HO) and the potential of HO as a target in anticancer treatment.
Fang J, Akaike T, Maeda H. Fang J, et al. Apoptosis. 2004 Jan;9(1):27-35. doi: 10.1023/B:APPT.0000012119.83734.4e. Apoptosis. 2004. PMID: 14739596 Review.
In addition, HO-1-deficient mice exhibit a significant increase in susceptibility to tissue injury. ...CO may produce an antiapoptotic effect by inhibiting both expression of p53 and release of mitochondrial cytochrome c. HO-1 may also be a target in antitumor thera …
In addition, HO-1-deficient mice exhibit a significant increase in susceptibility to tissue injury. ...CO may produce an antiapoptoti …
Heterotopic ossification.
Shehab D, Elgazzar AH, Collier BD. Shehab D, et al. J Nucl Med. 2002 Mar;43(3):346-53. J Nucl Med. 2002. PMID: 11884494 Free article. Review.
Heterotopic ossification (HO) is the presence of bone in soft tissue where bone normally does not exist. ...Before therapy begins, bone scanning may be requested to confirm the diagnosis of HO. In addition, surgical resection of HO is used to preserve joint m …
Heterotopic ossification (HO) is the presence of bone in soft tissue where bone normally does not exist. ...Before therapy begins, bo …
The role of miRNA and lncRNA in heterotopic ossification pathogenesis.
Pulik Ł, Mierzejewski B, Sibilska A, Grabowska I, Ciemerych MA, Łęgosz P, Brzóska E. Pulik Ł, et al. Stem Cell Res Ther. 2022 Dec 15;13(1):523. doi: 10.1186/s13287-022-03213-3. Stem Cell Res Ther. 2022. PMID: 36522666 Free PMC article. Review.
Heterotopic ossification (HO) is the formation of bone in non-osseous tissues, such as skeletal muscles. The HO could have a genetic or a non-genetic (acquired) background, that is, it could be caused by musculoskeletal trauma, such as burns, fractures, joint arthro …
Heterotopic ossification (HO) is the formation of bone in non-osseous tissues, such as skeletal muscles. The HO could have a g …
147,676 results
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