Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression.
Fishbein A, Wang W, Yang H, Yang J, Hallisey VM, Deng J, Verheul SML, Hwang SH, Gartung A, Wang Y, Bielenberg DR, Huang S, Kieran MW, Hammock BD, Panigrahy D.
Fishbein A, et al.
Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21576-21587. doi: 10.1073/pnas.2007412117. Epub 2020 Aug 14.
Proc Natl Acad Sci U S A. 2020.
PMID: 32801214
Free PMC article.
While eicosanoid and cytokine storms are well-characterized in infection and inflammation, they are poorly characterized in cancer. Here, we demonstrate that carcinogens, such as aflatoxin B(1) (AFB(1)), induce apoptotic cell death and the resulting cell debris stimulates …
While eicosanoid and cytokine storms are well-characterized in infection and inflammation, they are poorly characterized in cancer. Here, we …