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Year Number of Results
1975 1
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1993 3
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1995 1
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2001 4
2002 7
2003 7
2004 6
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2009 9
2010 5
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Page 1
OMIP-079: Cell cycle of CD4+ and CD8+ naïve/memory T cell subsets, and of Treg cells from mouse spleen.
Natalini A, Simonetti S, Favaretto G, Peruzzi G, Antonangeli F, Santoni A, Muñoz-Ruiz M, Hayday A, Di Rosa F. Natalini A, et al. Cytometry A. 2021 Dec;99(12):1171-1175. doi: 10.1002/cyto.a.24509. Epub 2021 Oct 19. Cytometry A. 2021. PMID: 34668313 Free PMC article.
In each T cell subset, a dual staining for Ki-67 expression and DNA content was employed to distinguish the following cell cycle phases: G(0) (Ki67(-) , with 2n DNA), G(1) (Ki67(+) , with 2n DNA), and S-G(2) /M (Ki67(+) , with 2n < DNA 4n). ...
In each T cell subset, a dual staining for Ki-67 expression and DNA content was employed to distinguish the following cell cycle phases: …
Identification of a β-arrestin-biased negative allosteric modulator for the β2-adrenergic receptor.
Ippolito M, De Pascali F, Hopfinger N, Komolov KE, Laurinavichyute D, Reddy PAN, Sakkal LA, Rajkowski KZ, Nayak AP, Lee J, Lee J, Cao G, Donover PS, Reichman M, An SS, Salvino JM, Penn RB, Armen RS, Scott CP, Benovic JL. Ippolito M, et al. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2302668120. doi: 10.1073/pnas.2302668120. Epub 2023 Jul 25. Proc Natl Acad Sci U S A. 2023. PMID: 37490535 Free PMC article.
Thus, the ability to bias beta(2)AR signaling toward the G(s) pathway while avoiding beta-arrestin-mediated effects may provide a strategy to improve the functional consequences of beta(2)AR activation. Since attempts to develop G(s)-biased agonists and allosteric m …
Thus, the ability to bias beta(2)AR signaling toward the G(s) pathway while avoiding beta-arrestin-mediated effects may provide a str …
Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies.
Schaefer W, Regula JT, Bähner M, Schanzer J, Croasdale R, Dürr H, Gassner C, Georges G, Kettenberger H, Imhof-Jung S, Schwaiger M, Stubenrauch KG, Sustmann C, Thomas M, Scheuer W, Klein C. Schaefer W, et al. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11187-92. doi: 10.1073/pnas.1019002108. Epub 2011 Jun 20. Proc Natl Acad Sci U S A. 2011. PMID: 21690412 Free PMC article.
Protein kinase G oxidation is a major cause of injury during sepsis.
Rudyk O, Phinikaridou A, Prysyazhna O, Burgoyne JR, Botnar RM, Eaton P. Rudyk O, et al. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9909-13. doi: 10.1073/pnas.1301026110. Epub 2013 May 28. Proc Natl Acad Sci U S A. 2013. PMID: 23716652 Free PMC article.
Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein alpha-subunit.
Thomas CJ, Du X, Li P, Wang Y, Ross EM, Sprang SR. Thomas CJ, et al. Proc Natl Acad Sci U S A. 2004 May 18;101(20):7560-5. doi: 10.1073/pnas.0304091101. Epub 2004 May 5. Proc Natl Acad Sci U S A. 2004. PMID: 15128951 Free PMC article.
Heterotrimeric G protein alpha (G alpha) subunits possess intrinsic GTPase activity that leads to functional deactivation with a rate constant of approximately 2 min(-1) at 30 degrees C. ...Mutation of K180-->P in Switch I increases the rate of conformational cha …
Heterotrimeric G protein alpha (G alpha) subunits possess intrinsic GTPase activity that leads to functional deactivation with …
Efficacy and Safety of Elamipretide in Individuals With Primary Mitochondrial Myopathy: The MMPOWER-3 Randomized Clinical Trial.
Karaa A, Bertini E, Carelli V, Cohen BH, Enns GM, Falk MJ, Goldstein A, Gorman GS, Haas R, Hirano M, Klopstock T, Koenig MK, Kornblum C, Lamperti C, Lehman A, Longo N, Molnar MJ, Parikh S, Phan H, Pitceathly RDS, Saneto R, Scaglia F, Servidei S, Tarnopolsky M, Toscano A, Van Hove JLK, Vissing J, Vockley J, Finman JS, Brown DA, Shiffer JA, Mancuso M; MMPOWER-3 Trial Investigators. Karaa A, et al. Neurology. 2023 Jul 18;101(3):e238-e252. doi: 10.1212/WNL.0000000000207402. Epub 2023 Jun 2. Neurology. 2023. PMID: 37268435 Free PMC article. Clinical Trial.
Pathogenic TNF-α drives peripheral nerve inflammation in an Aire-deficient model of autoimmunity.
Wang Y, Guo L, Yin X, McCarthy EC, Cheng MI, Hoang AT, Chen HC, Patel AY, Allard Trout D, Xu E, Yakobian N, Hugo W, Howard JF Jr, Sheu KM, Hoffmann A, Lechner MG, Su MA. Wang Y, et al. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2114406119. doi: 10.1073/pnas.2114406119. Proc Natl Acad Sci U S A. 2022. PMID: 35058362 Free PMC article.
After injury, immune cells are reparative, while in inflammatory neuropathies (e.g., Guillain Barre Syndrome and chronic inflammatory demyelinating polyneuropathy), immune cells are proinflammatory and promote autoimmune demyelination. ...
After injury, immune cells are reparative, while in inflammatory neuropathies (e.g., Guillain Barre Syndrome and chronic inflammatory …
Statistical signature of electrobreakdown in graphene nanojunctions.
Evangeli C, Tewari S, Kruip JM, Bian X, Swett JL, Cully J, Thomas J, Briggs GAD, Mol JA. Evangeli C, et al. Proc Natl Acad Sci U S A. 2022 Jul 5;119(27):e2119015119. doi: 10.1073/pnas.2119015119. Epub 2022 Jun 27. Proc Natl Acad Sci U S A. 2022. PMID: 35759664 Free PMC article.
We show that when the conductance of the graphene becomes smaller than around 0.1 G(0), the effective graphene notch width starts to decrease exponentially slower with time. ...
We show that when the conductance of the graphene becomes smaller than around 0.1 G(0), the effective graphene notch width starts to …
Associations between light exposure and sleep timing and sleepiness while awake in a sample of UK adults in everyday life.
Didikoglu A, Mohammadian N, Johnson S, van Tongeren M, Wright P, Casson AJ, Brown TM, Lucas RJ. Didikoglu A, et al. Proc Natl Acad Sci U S A. 2023 Oct 17;120(42):e2301608120. doi: 10.1073/pnas.2301608120. Epub 2023 Oct 9. Proc Natl Acad Sci U S A. 2023. PMID: 37812713 Free PMC article.
We use it to simultaneously record longitudinal light exposure (in melanopic equivalent daylight illuminance), sleep timing, and subjective alertness over seven days in a convenience sample of 59 UK adults without externally imposed circadian challenge (e.g., shift work or …
We use it to simultaneously record longitudinal light exposure (in melanopic equivalent daylight illuminance), sleep timing, and subjective …
210 results