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Year Number of Results
2011 1
2012 1
2014 1
2015 2
2016 4
2017 3
2018 5
2019 3
2020 5
2021 2
2022 2
2024 0

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28 results

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Page 1
Monitoring TRPC7 Conformational Changes by BRET Following GPCR Activation.
Pétigny C, Dumont AA, Giguère H, Collette A, Holleran BJ, Iftinca M, Altier C, Besserer-Offroy É, Auger-Messier M, Leduc R. Pétigny C, et al. Among authors: besserer offroy e. Int J Mol Sci. 2022 Feb 24;23(5):2502. doi: 10.3390/ijms23052502. Int J Mol Sci. 2022. PMID: 35269644 Free PMC article.
Size-Reduced Macrocyclic Analogues of [Pyr1]-apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac Effects.
Tran K, Sainsily X, Côté J, Coquerel D, Couvineau P, Saibi S, Haroune L, Besserer-Offroy É, Flynn-Robitaille J, Resua Rojas M, Murza A, Longpré JM, Auger-Messier M, Lesur O, Bouvier M, Marsault É, Boudreault PL, Sarret P. Tran K, et al. Among authors: besserer offroy e. J Med Chem. 2022 Jan 13;65(1):531-551. doi: 10.1021/acs.jmedchem.1c01708. Epub 2022 Jan 4. J Med Chem. 2022. PMID: 34982553
In Search of the Optimal Macrocyclization Site for Neurotensin.
Sousbie M, Besserer-Offroy É, Brouillette RL, Longpré JM, Leduc R, Sarret P, Marsault É. Sousbie M, et al. Among authors: besserer offroy e. ACS Med Chem Lett. 2018 Jan 29;9(3):227-232. doi: 10.1021/acsmedchemlett.7b00500. eCollection 2018 Mar 8. ACS Med Chem Lett. 2018. PMID: 29541365 Free PMC article.
Structural insights on ligand recognition at the human leukotriene B4 receptor 1.
Michaelian N, Sadybekov A, Besserer-Offroy É, Han GW, Krishnamurthy H, Zamlynny BA, Fradera X, Siliphaivanh P, Presland J, Spencer KB, Soisson SM, Popov P, Sarret P, Katritch V, Cherezov V. Michaelian N, et al. Among authors: besserer offroy e. Nat Commun. 2021 May 20;12(1):2971. doi: 10.1038/s41467-021-23149-1. Nat Commun. 2021. PMID: 34016973 Free PMC article.
Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs.
Luginina A, Gusach A, Marin E, Mishin A, Brouillette R, Popov P, Shiriaeva A, Besserer-Offroy É, Longpré JM, Lyapina E, Ishchenko A, Patel N, Polovinkin V, Safronova N, Bogorodskiy A, Edelweiss E, Hu H, Weierstall U, Liu W, Batyuk A, Gordeliy V, Han GW, Sarret P, Katritch V, Borshchevskiy V, Cherezov V. Luginina A, et al. Among authors: besserer offroy e. Sci Adv. 2019 Oct 9;5(10):eaax2518. doi: 10.1126/sciadv.aax2518. eCollection 2019 Oct. Sci Adv. 2019. PMID: 31633023 Free PMC article.
Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors.
Gusach A, Luginina A, Marin E, Brouillette RL, Besserer-Offroy É, Longpré JM, Ishchenko A, Popov P, Patel N, Fujimoto T, Maruyama T, Stauch B, Ergasheva M, Romanovskaia D, Stepko A, Kovalev K, Shevtsov M, Gordeliy V, Han GW, Katritch V, Borshchevskiy V, Sarret P, Mishin A, Cherezov V. Gusach A, et al. Among authors: besserer offroy e. Nat Commun. 2019 Dec 6;10(1):5573. doi: 10.1038/s41467-019-13348-2. Nat Commun. 2019. PMID: 31811124 Free PMC article.
Structure-Activity Relationship and Signaling of New Chimeric CXCR4 Agonists.
Mona CE, Besserer-Offroy É, Cabana J, Lefrançois M, Boulais PE, Lefebvre MR, Leduc R, Lavigne P, Heveker N, Marsault É, Escher E. Mona CE, et al. Among authors: besserer offroy e. J Med Chem. 2016 Aug 25;59(16):7512-24. doi: 10.1021/acs.jmedchem.6b00566. Epub 2016 Aug 11. J Med Chem. 2016. PMID: 27434274
Cell-penetrating pepducins targeting the neurotensin receptor type 1 relieve pain.
Brouillette RL, Besserer-Offroy É, Mona CE, Chartier M, Lavenus S, Sousbie M, Belleville K, Longpré JM, Marsault É, Grandbois M, Sarret P. Brouillette RL, et al. Among authors: besserer offroy e. Pharmacol Res. 2020 May;155:104750. doi: 10.1016/j.phrs.2020.104750. Epub 2020 Mar 6. Pharmacol Res. 2020. PMID: 32151680
28 results