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TNF and IL6/Jak2 signaling pathways are the main contributors of the glia-derived neuroinflammation present in Lafora disease, a fatal form of progressive myoclonus epilepsy.
Neurobiol Dis. 2023 Jan;176:105964. doi: 10.1016/j.nbd.2022.105964. Epub 2022 Dec 14.
Neurobiol Dis. 2023.
PMID: 36526090
Free PMC article.
Deciphering the Polyglucosan Accumulation Present in Lafora Disease Using an Astrocytic Cellular Model.
Moreno-Estellés M, Campos-Rodríguez Á, Rubio-Villena C, Kumarasinghe L, Garcia-Gimeno MA, Sanz P.
Moreno-Estellés M, et al. Among authors: campos rodriguez a.
Int J Mol Sci. 2023 Mar 23;24(7):6020. doi: 10.3390/ijms24076020.
Int J Mol Sci. 2023.
PMID: 37046993
Free PMC article.
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Beneficial Effect of Fingolimod in a Lafora Disease Mouse Model by Preventing Reactive Astrogliosis-Derived Neuroinflammation and Brain Infiltration of T-lymphocytes.
Rubio T, Campos-Rodríguez Á, Sanz P.
Rubio T, et al. Among authors: campos rodriguez a.
Mol Neurobiol. 2024 Jun;61(6):3105-3120. doi: 10.1007/s12035-023-03766-1. Epub 2023 Nov 16.
Mol Neurobiol. 2024.
PMID: 37971656
Free PMC article.
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