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Underrepresented Populations in Pediatric Epilepsy Surgery.
Armour EA, Yiu AJ, Shrey DW, Reddy SB. Armour EA, et al. Semin Pediatr Neurol. 2021 Oct;39:100916. doi: 10.1016/j.spen.2021.100916. Epub 2021 Aug 20. Semin Pediatr Neurol. 2021. PMID: 34620462 Free article. Review.
A Case Report on Pregabalin-Induced Eosinophilia.
Shilpa R, Sreekrishnan TP, Kumar KPG, Neethu CM. Shilpa R, et al. Consult Pharm. 2018 Jun 1;33(6):317-320. doi: 10.4140/TCP.n.2018.317. Consult Pharm. 2018. PMID: 29880093
BACKGROUND: Pregabalin, a structural derivative of the inhibitory neurotransmitter gamma amino butyric acid, has antiepileptic, analgesic, and anxiolytic properties; therefore, it is used for painful diabetic neuropathy, postherpetic neuralgia, fibromyalgia, and neuropathic pain …
BACKGROUND: Pregabalin, a structural derivative of the inhibitory neurotransmitter gamma amino butyric acid, has antiepileptic, analgesic, a …
Evaluation of GABA-chitosan nanoparticle induced cell signaling activation during liver regeneration after partial hepatectomy.
Shilpa J, Naijil G, Nandhu MS, Paulose CS. Shilpa J, et al. J Nanosci Nanotechnol. 2012 Aug;12(8):6145-55. doi: 10.1166/jnn.2012.6194. J Nanosci Nanotechnol. 2012. PMID: 22962720
The interaction of GABA-chitosan nanoparticles with hepatocytes were observed by FITC labeled nanoparticles. After partial hepatectomy in male Wistar rats, DNA synthesis was estimated by tritiated thymidine uptake and the activity of thymidine kinase and protein synthesis …
The interaction of GABA-chitosan nanoparticles with hepatocytes were observed by FITC labeled nanoparticles. After partial hepatectom …
Eftozanermin alfa (ABBV-621) monotherapy in patients with previously treated solid tumors: findings of a phase 1, first-in-human study.
LoRusso P, Ratain MJ, Doi T, Rasco DW, de Jonge MJA, Moreno V, Carneiro BA, Devriese LA, Petrich A, Modi D, Morgan-Lappe S, Nuthalapati S, Motwani M, Dunbar M, Glasgow J, Medeiros BC, Calvo E. LoRusso P, et al. Invest New Drugs. 2022 Aug;40(4):762-772. doi: 10.1007/s10637-022-01247-1. Epub 2022 Apr 25. Invest New Drugs. 2022. PMID: 35467243 Free PMC article. Clinical Trial.
In the dose-optimization cohort, three patients (CRC, n = 2; PaCA, n = 1) had a partial response. Target engagement with regard to receptor saturation, and downstream apoptotic pathway activation in circulation and tumor were observed. ...
In the dose-optimization cohort, three patients (CRC, n = 2; PaCA, n = 1) had a partial response. Target engagement with regard to re …
Multivariate curve resolution -alternating least squares augmented with partial least squares baseline correction applied to mid-IR laser spectra resolves protein denaturation by reducing rotational ambiguity.
Vijayakumar S, Schwaighofer A, Ramer G, Lendl B. Vijayakumar S, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2024 Jul 5;315:124228. doi: 10.1016/j.saa.2024.124228. Epub 2024 Mar 30. Spectrochim Acta A Mol Biomol Spectrosc. 2024. PMID: 38593537 Free article.
In this work, the use of multivariate curve resolution alternating least squares (MCR-ALS) for the analysis of a chemical de- and renaturation experiment has been demonstrated, since this technique offers the second-order advantage of extracting spectral signatures and concentrat …
In this work, the use of multivariate curve resolution alternating least squares (MCR-ALS) for the analysis of a chemical de- and renaturati …
Longitudinal clinico-serological analysis of anti-nucleocapsid and anti-receptor binding domain of spike protein antibodies against SARS-CoV-2.
Deshpande GR, Kaduskar O, Deshpande K, Bhatt V, Yadav P, Gurav Y, Potdar V, Khutwad K, Vidhate S, Salunke A, Patil C, Shingade S, Jarande K, Tilekar B, Salvi P, Patsuthe S, Dange V, Kumar S, Gurav S, Chate S, Abraham P, Sapkal G. Deshpande GR, et al. Int J Infect Dis. 2021 Nov;112:103-110. doi: 10.1016/j.ijid.2021.09.024. Epub 2021 Sep 17. Int J Infect Dis. 2021. PMID: 34543771 Free PMC article.
RESULTS: A steep increase in antigen specific antibody titers was observed till 40 days post onset of the disease (POD), followed by a partial decline till 240 days. Severe disease was associated with a stronger SRBD IgG response and higher NAb titers. ...
RESULTS: A steep increase in antigen specific antibody titers was observed till 40 days post onset of the disease (POD), followed by a pa …
Clinical spectrum of adult patients with annular pancreas: Findings from a large single institution cohort.
Nagpal SJS, Peeraphatdit T, Sannapaneni SK, Sharma A, Takahashi N, Kendrick ML, Majumder S, Vege SS. Nagpal SJS, et al. Pancreatology. 2019 Mar;19(2):290-295. doi: 10.1016/j.pan.2018.12.009. Epub 2019 Jan 3. Pancreatology. 2019. PMID: 30660391
BACKGROUND AND AIMS: Annular pancreas (AnnP) is a rare congenital abnormality that results from the presence of a complete or partial ring of pancreatic tissue surrounding the descending portion of the duodenum. ...
BACKGROUND AND AIMS: Annular pancreas (AnnP) is a rare congenital abnormality that results from the presence of a complete or partial …
A Phase I Trial of Combined Ridaforolimus and MK-2206 in Patients with Advanced Malignancies.
Gupta S, Argilés G, Munster PN, Hollebecque A, Dajani O, Cheng JD, Wang R, Swift A, Tosolini A, Piha-Paul SA. Gupta S, et al. Clin Cancer Res. 2015 Dec 1;21(23):5235-44. doi: 10.1158/1078-0432.CCR-15-0180. Epub 2015 Jul 17. Clin Cancer Res. 2015. PMID: 26187616 Clinical Trial.
By investigator assessment, 2 of 16 (12.5%) evaluable patients with breast cancer had partial response; by central assessment, 2 of 14 (14.3%) evaluable patients had complete response. ...
By investigator assessment, 2 of 16 (12.5%) evaluable patients with breast cancer had partial response; by central assessment, 2 of 1 …
Phase II trial of the anti-CD19 bispecific T cell-engager blinatumomab shows hematologic and molecular remissions in patients with relapsed or refractory B-precursor acute lymphoblastic leukemia.
Topp MS, Gökbuget N, Zugmaier G, Klappers P, Stelljes M, Neumann S, Viardot A, Marks R, Diedrich H, Faul C, Reichle A, Horst HA, Brüggemann M, Wessiepe D, Holland C, Alekar S, Mergen N, Einsele H, Hoelzer D, Bargou RC. Topp MS, et al. J Clin Oncol. 2014 Dec 20;32(36):4134-40. doi: 10.1200/JCO.2014.56.3247. Epub 2014 Nov 10. J Clin Oncol. 2014. PMID: 25385737 Clinical Trial.
The primary end point was complete remission (CR) or CR with partial hematologic recovery (CRh). Major secondary end points included minimal residual disease (MRD) response, rate of allogeneic hematopoietic stem-cell transplantation (HSCT) realization, relapse-free surviva …
The primary end point was complete remission (CR) or CR with partial hematologic recovery (CRh). Major secondary end points included …
15 results