Exploiting a Y chromosome-linked Cas9 for sex selection and gene drive.
Gamez S, Chaverra-Rodriguez D, Buchman A, Kandul NP, Mendez-Sanchez SC, Bennett JB, Sánchez C HM, Yang T, Antoshechkin I, Duque JE, Papathanos PA, Marshall JM, Akbari OS.
Gamez S, et al.
Nat Commun. 2021 Dec 10;12(1):7202. doi: 10.1038/s41467-021-27333-1.
Nat Commun. 2021.
PMID: 34893590
Free PMC article.
XY, ZW), sex linkage of endonucleases could be beneficial to drive the expression in a sex-specific manner to produce genetic sexing systems, sex ratio distorters, or even sex-specific gene drives, for example. ...
XY, ZW), sex linkage of endonucleases could be beneficial to drive the expression in a sex-specific manner to produce genetic sexing …