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Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer's disease-relevant murine model.
Long AN, Owens K, Schlappal AE, Kristian T, Fishman PS, Schuh RA. Long AN, et al. BMC Neurol. 2015 Mar 1;15:19. doi: 10.1186/s12883-015-0272-x. BMC Neurol. 2015. PMID: 25884176 Free PMC article.
BACKGROUND: Mitochondrial dysfunction is a hallmark of neurodegenerative diseases including Alzheimer's disease (AD), with morphological and functional abnormalities limiting the electron transport chain and ATP production. ...
BACKGROUND: Mitochondrial dysfunction is a hallmark of neurodegenerative diseases including Alzheimer's disease (AD), with morphologi …
Traditional Chinese Medicine Compounds Containing Lonicera japonica, Chrysanthemum morifolium, and Siraitia grosvenorii Inhibits the Growth of Streptococcus mutans.
Zhou X, Reheman A, Kang Z, Long A, Wang T. Zhou X, et al. Among authors: long a. Evid Based Complement Alternat Med. 2022 Oct 13;2022:5802343. doi: 10.1155/2022/5802343. eCollection 2022. Evid Based Complement Alternat Med. 2022. PMID: 36276853 Free PMC article.
The antibacterial activities of Lonicera japonica, Chrysanthemum morifolium, and Siraitia grosvenorii on Streptococcus mutans (S. mutans) UA159 was measured. Lonicera japonica (40 mg/mL), Chrysanthemum morifolium (10 mg/mL), and Siraitia grosvenorii (10 mg/mL) effectively …
The antibacterial activities of Lonicera japonica, Chrysanthemum morifolium, and Siraitia grosvenorii on Streptococcus mutans (S. mut …
LMR-101, a novel derivative of propofol, exhibits potent anticonvulsant effects and possibly interacts with a novel target on γ-aminobutyric acid type A receptors.
Zhao Y, An L, Guo S, Huang X, Tian H, Liu L, Chen T, Sun X, Mei Q, Wang R. Zhao Y, et al. Among authors: an l. Epilepsia. 2021 Jan;62(1):238-249. doi: 10.1111/epi.16757. Epub 2021 Jan 8. Epilepsia. 2021. PMID: 33417274
The median effective dose for LMR-101 was 14.30 mg/kg and 121.87 mg/kg to prevent and inhibit sustained SE, respectively. In binding assays, LMR-101 primarily inhibited tert-[(35) S] butylbicyclophosphorothionate binding to gamma-aminobutyric acid type A (GABA(A) ) recepto …
The median effective dose for LMR-101 was 14.30 mg/kg and 121.87 mg/kg to prevent and inhibit sustained SE, respectively. In binding assays, …