Pyoderma gangrenosum, acne, suppurative hidradenitis (PASH) and polycystic ovary syndrome: Coincidentally or aetiologically connected?

Dubravka Zivanovic; Iva Masirevic; Thomas Ruzicka; Markus Braun-Falco; Milos Nikolic

doi:10.1111/ajd.12438

Pyoderma gangrenosum, acne, suppurative hidradenitis (PASH) and polycystic ovary syndrome: Coincidentally or aetiologically connected?

Australas J Dermatol. 2017 May;58(2):e54-e59. doi: 10.1111/ajd.12438. Epub 2016 Feb 2.

Authors

Dubravka Zivanovic^{1

2}, Iva Masirevic¹, Thomas Ruzicka³, Markus Braun-Falco³, Milos Nikolic^{1

2}

Affiliations

¹ Clinic of Dermatovenereology, Clinical Centre of Serbia, Belgrade, Serbia.
² Department of Dermatovenereology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
³ Department of Dermatology, Ludwig-Maximilian University Munich, Munich, Germany.

PMID: 26831949
DOI: 10.1111/ajd.12438

Abstract

The clinical triad of pyoderma gangrenosum, acne conglobata and hidradenitis suppurativa has been named PASH syndrome. Polycystic ovary syndrome (PCOS) is associated with hyperandrogenism and inflammation. Hidradenitis suppurativa, like acne vulgaris, may be a feature of hyperandrogenism. Obesity may be associated with both hidradenitis suppurativa and PCOS. We describe a possible association between PASH syndrome and PCOS.

Keywords: PCOS; PASH syndrome; autoinflammatory diseases; hidradenitis suppurativa; pyoderma gangrenosum.

Publication types

Case Reports

MeSH terms

Acne Vulgaris / complications*
Adult
Female
Hidradenitis Suppurativa / complications*
Humans
Polycystic Ovary Syndrome / complications*
Pyoderma Gangrenosum / complications*
Syndrome